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alpha-methylepinine
Known as:
3,4-dihydroxymethamphetamine
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Deoxyepinephrine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Contribution of Cytochrome P450 2D6 to 3,4-Methylenedioxymethamphetamine Disposition in Humans
M. Segura
,
M. Farré
,
+8 authors
R. Torre
Clinical Pharmacokinetics
2005
Corpus ID: 26218068
AbstractBackground: 3,4-Methylenedioxymethamphetamine (MDMA) is a synthetic amphetamine derivative typically used for…
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Highly Cited
2005
Highly Cited
2005
A comparative study on the acute and long‐term effects of MDMA and 3,4‐dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice
I. Escobedo
,
E. O'Shea
,
+6 authors
M. Colado
British Journal of Pharmacology
2005
Corpus ID: 45948624
1 This study investigated whether the immediate and long‐term effects of 3,4‐methylenedioxymethamphetamine (MDMA) on monoamines…
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Highly Cited
2004
Highly Cited
2004
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites in human samples including the catechol-type metabolite (3,4-dihydroxymethamphetamine).
N. Pizarro
,
M. Farré
,
+4 authors
R. de la Torre
Drug Metabolism And Disposition
2004
Corpus ID: 8611372
3,4-Methylenedioxymethamphetamine (MDMA; "ecstasy") is a designer drug commonly misused in large segments of young populations…
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2004
2004
Influence of phenylalanine 120 on cytochrome P450 2D6 catalytic selectivity and regiospecificity: crucial role in 7-methoxy-4-(aminomethyl)-coumarin metabolism.
P. Keizers
,
B. Lussenburg
,
C. de Graaf
,
L. Mentink
,
N. Vermeulen
,
J. Commandeur
Biochemical Pharmacology
2004
Corpus ID: 42086778
2002
2002
Action of MDMA (Ecstasy) and Its Metabolites on Arginine Vasopressin Release
J. K. Fallon
,
D. Shah
,
+4 authors
M. Forsling
Annals of the New York Academy of Sciences
2002
Corpus ID: 7992553
Abstract: 3,4‐Methylenedioxymethamphetamine (MDMA) has been reported to cause hyponatraemia, which appears to result from…
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Highly Cited
2001
Highly Cited
2001
3,4-Dihydroxymethamphetamine (HHMA). A major in vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans.
M. Segura
,
J. Ortuño
,
+8 authors
R. de la Torre
Chemical Research in Toxicology
2001
Corpus ID: 25470897
There is evidence that some heavy users of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) show signs of neurotoxicity (a…
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Highly Cited
1996
Highly Cited
1996
Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion.
T. Chu
,
Y. Kumagai
,
E. Distefano
,
A. Cho
Biochemical Pharmacology
1996
Corpus ID: 33950927
Highly Cited
1990
Highly Cited
1990
Metabolism of methylenedioxymethamphetamine: formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct.
M. Hiramatsu
,
Y. Kumagai
,
S. Unger
,
A. Cho
Journal of Pharmacology and Experimental…
1990
Corpus ID: 23178101
The in vitro conversion of (+)-3,4-methylenedioxymethamphetamine and (-)-3,4-methylenedioxymethamphetamine to the corresponding…
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Highly Cited
1990
Highly Cited
1990
Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis.
A. Cho
,
M. Hiramatsu
,
E. Distefano
,
A. Chang
,
D. Jenden
Drug Metabolism And Disposition
1990
Corpus ID: 24303906
The in vivo N-demethylation of (+) and (-)3,4-methylenedioxymethamphetamine (MDMA) to 3,4-methylenedioxyamphetamine (MDA) was…
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Highly Cited
1988
Highly Cited
1988
In vivo and in vitro metabolism of 3,4-(methylenedioxy)methamphetamine in the rat: identification of metabolites using an ion trap detector.
H. Lim
,
R. Foltz
Chemical Research in Toxicology
1988
Corpus ID: 5669773
Four biotransformation pathways of 3,4-(methylenedioxy)methamphetamine (MDMA) in the rat have been identified: N-demethylation, O…
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