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alpha-ketoglutarate dehydrogenase complex location (sensu Eukarya)

Known as: mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrial alpha-ketoglutarate dehydrogenase complex location 
Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity. [GOC:mah, GOC:mtg_sensu]
National Institutes of Health

Related topics

Related topics

3 relations
Ketoglutarate Dehydrogenase Complexdihydrolipoyl dehydrogenase complex location

Broader (1)

Mitochondria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
An update on the role of mitochondrial α-ketoglutarate dehydrogenase in oxidative stress
The activity of mitochondrial alpha-ketoglutarate dehydrogenase complex (KGDHC) is severely reduced in human pathologies where… Expand
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2007
2007
Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability
Thiamine-dependent enzymes are diminished in multiple neurodegenerative diseases. Thiamine deficiency (TD) reduces the activity… Expand
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2004
2004
Alpha-Ketoglutarate dehydrogenase and lipoic acid synthase are important for the functioning of peroxisomes of Saccharomyces cerevisiae.
A method was devised to search for yeast mutants impaired in peroxisome functioning, indicating cross-talk between metabolic… Expand
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2002
2002
Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme.
Fibroblasts from patients with genetic and non-genetic forms of Alzheimer's disease (AD) show many abnormalities including… Expand
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2001
2001
No association between DLST gene and Alzheimer’s disease or Wernicke-Korsakoff syndrome
Among many candidate genes for the genetically heterogeneous Alzheimer's disease (AD), only apolipoprotein E (ApoE) has been… Expand
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1999
1999
A DLST genotype associated with reduced risk for Alzheimer's disease.
Recent studies suggest that variants of the DLST gene alter the risk of AD. DLST encodes the core subunit of the mitochondrial… Expand
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1999
1999
Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population.
The mitochondrial alpha-ketoglutarate dehydrogenase complex (KGDHC) is deficient in Alzheimer's disease (AD). The DLST gene… Expand
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Highly Cited
1994
Highly Cited
1994
An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease.
We report an immunohistochemical study of the mitochondrial alpha-ketoglutarate dehydrogenase complex (KGDHC) in the substantia… Expand
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1991
1991
In vivo assembly of yeast mitochondrial alpha-ketoglutarate dehydrogenase complex.
The assembly of alpha-ketoglutarate dehydrogenase complex (KGDC) has been studied in wild-type Saccharomyces cerevisiae and in… Expand
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1989
1989
Structure and regulation of KGD1, the structural gene for yeast alpha-ketoglutarate dehydrogenase.
Nuclear respiratory-defective mutants of Saccharomyces cerevisiae have been screened for lesions in the mitochondrial alpha… Expand
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