alpha-galactosylceramide

Known as: Alpha Galactosylceramide, a-GalCer, alpha-GalCer 
A drug being studied in the treatment of cancer. It is a biological response modifier that belongs to the family of drugs called glycosphingolipids… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Activation of innate immunity is critical for vaccine development and immunotherapy, through triggering antigen specific immune… (More)
Is this relevant?
2009
2009
Development of mucosal adjuvants to generate immunity in the female genital tract may have important implications for the… (More)
  • figure 1
  • table I
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
2008
2008
BACKGROUND Human Valpha24 natural killer T (NKT) cells are activated by the specific ligand, alpha-galactosylceramide (alpha… (More)
Is this relevant?
2007
2007
alpha-Galactosylceramide (alpha-GalCer), originally isolated from a marine sponge, was known to activate natural killer T (NKT… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
PURPOSE Human Valpha24 natural killer T (NKT) cells bearing an invariant Valpha24JalphaQ antigen receptor, the counterpart of… (More)
Is this relevant?
2005
2005
To clarify the essential role of NKT cells in allergy, we investigated the contribution of NKT cells to the pathogenesis of… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Invariant natural killer T (NKT) cells are a highly conserved subset of T lymphocytes expressing a semi-invariant T cell receptor… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Natural killer T (NKT) cells have an extremely restricted T-cell receptor repertoire, in man consisting of a Valpha24 chain… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
We have compared the immune responses of mice immunized either with alpha-galactosylceramide (alpha-GalCer), capable of eliciting… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Colorectal liver metastasis is clinically a major problem. We examined the antitumor activity of KRN7000, an alpha… (More)
Is this relevant?