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alpha-galactosylceramide

Known as: Alpha Galactosylceramide, a-GalCer, alpha-GalCer 
A drug being studied in the treatment of cancer. It is a biological response modifier that belongs to the family of drugs called glycosphingolipids… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Galactosylceramides
KRN 7000NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Research in Immune Receptors & Signaling
Using our transgenic model of primary HBV infection, we established that that non-classical NKT cells that are CD1d-restricted… 
2016
2016
Assessment of combined vaccination and immune modulation as an anti-tumour therapy
Glioblastoma multiforme (GBM) is a common and lethal type of brain cancer, with a very poor prognosis. Current therapy consisting… 
2016
2016
Estructura y función del complejo TCR-CD3 en las deficiencias congénitas y adquiridas ("knock-down") de CD3
Las inmunodeficiencias primarias asociadas al complejo TCR/CD3 son enfermedades autosomicas recesivas muy raras en las que la… 
2012
2012
Cancer Therapy : Preclinical Vaccination with Irradiated Tumor Cells Pulsed with an Adjuvant That Stimulates NKTCells Is an Effective Treatment for Glioma
Purpose: The prognosis for patients with glioblastoma multiforme (GBM) remains extremely poor despite recent treatment advances… 
2009
2009
Viral Infection Protective Immunity to Sexually Transmitted-Galactosylceramide for Induction of α The Mucosal Adjuvant Effect of
2009
2009
Ameliorates ConA-Induced Hepatitis Regulates Cytokine Production and SOCS3 in T and NKT Cells Negatively
2†‡ Suppressor of cytokine signaling 3 (SOCS3), a negative-feedback molecule for cytokine signaling, has been implicated in… 
Review
2007
Review
2007
Effects of theAdministration of High-Dose Interleukin-2 on Immunoregulatory Cell Subsets in Patients with AdvancedMelanoma and Renal Cell Cancer
Purpose: High-dose recombinant human interleukin-2 (IL-2) therapy is of clinical benefit in a subset of patients with advanced… 
2005
2005
Distinct roles of dendritic cells and B cells in Va14Ja18 natural T (iNKT) cell activation in vivo
1999
1999
Advances in Brief Antitumor Cytotoxicity Mediated by Ligand-activated Human V a 24 NKT Cells 1
Human Va24 NKT cells bearing an invariant Va24JaQ antigen receptor, the counterpart of the murine Va14 NKT cells, are activated… 
Highly Cited
1998
Highly Cited
1998
Antitumor activity of alpha-galactosylceramide, KRN7000, in mice with EL-4 hepatic metastasis and its cytokine production.
Liver metastasis of primary tumor is a clinically major problem. KRN7000, an alpha-galactosylceramide, significantly augments… 
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