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alpha 1-Antitrypsin Deficiency

Known as: A1ATD, alpha 1-Antitrypsin Deficiencies, Deficiency, alpha 1-Antitrypsin 
A genetic disorder characterized by decreased alpha-1 antitrypsin activity in the lungs and blood and deposition of alpha-1 antitrypsin protein in… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Autophagy is a self-eating catabolic pathway that contributes to liver homeostasis through its role in energy balance and in the… Expand
Review
2008
Review
2008
Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder that manifests as pulmonary emphysema, liver cirrhosis and, rarely… Expand
Highly Cited
1991
Highly Cited
1991
The emphysema of alpha 1-antitrypsin (alpha 1AT) deficiency is conceptualized to result from insufficient alpha 1AT allowing… Expand
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Highly Cited
1988
Highly Cited
1988
Alpha-1-antitrypsin (alpha 1AT) deficiency is a hereditary disorder characterized in adults by a high risk for the development of… Expand
Highly Cited
1987
Highly Cited
1987
In patients with alpha 1-antitrypsin deficiency, the development of emphysema is believed to be caused by the unchecked action of… Expand
Highly Cited
1986
Highly Cited
1986
Previous reports have suggested an association between homozygous alpha 1-antitrypsin deficiency, cirrhosis, and primary liver… Expand
Highly Cited
1985
Highly Cited
1985
From 1970 to 1983, 69 individuals (aged from infancy to 87 years) with homozygous alpha 1-antitrypsin deficiency (ZZ) were… Expand
Highly Cited
1981
Highly Cited
1981
The emphysema associated with the inherited serum deficiency of alpha 1-antitrypsin appears to result from an imbalance between… Expand
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Highly Cited
1969
Highly Cited
1969
 
Highly Cited
1968
Highly Cited
1968
Abstract A genetically determined deficiency of alpha 1 -antitrypsin has been shown to be associated with pulmonary emphysema… Expand