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alpha,beta-methyleneadenosine 5'-triphosphate

Known as: 5'-(hydrogen((hydroxy(phosphonooxy)phosphinyl)methyl)phosphonate)adenosine, (.alpha.,.beta.-methylene)adenosine 5'-triphosphate, alpha,beta-methylene ATP 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Adenosine TriphosphateAntineoplastic Agents

Narrower (1)

alpha,beta-methyleneadenosine 5'-triphosphate, lithium salt
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Structural basis for substrate loading in bacterial RNA polymerase
The mechanism of substrate loading in multisubunit RNA polymerase is crucial for understanding the general principles of… 
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Highly Cited
2002
Highly Cited
2002
Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.
Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of diseases with excess… 
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Highly Cited
1999
Highly Cited
1999
Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs.
Recently, advances have been made in understanding the molecular mechanisms by which bisphosphonate drugs inhibit bone resorption… 
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Highly Cited
1998
Highly Cited
1998
Molecular Basis for ADP-induced Platelet Activation
ADP is an important platelet agonist causing shape change from smooth discoid shape to spiculated spheres and platelet… 
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Highly Cited
1996
Highly Cited
1996
Activation of Receptor-operated Cation Channels via P Not P Purinoceptors in Human Platelets (*)
We have investigated the purinoceptor subtypes responsible for calcium signaling in human platelets, which previous studies have… 
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Highly Cited
1996
Highly Cited
1996
Second messenger cascade specificity and pharmacological selectivity of the human P2Y1‐purinoceptor
1 . The coding sequence of the P2Y1‐purinoceptor was cloned from a human genomic library. 2 . The open reading frame encodes a… 
Highly Cited
1995
Highly Cited
1995
Pharmacological selectivity of the cloned human P2U‐purinoceptor: potent activation by diadenosine tetraphosphate
1 The human P2U‐purinoceptor was stably expressed in 1321N1 human astrocytoma cells and the pharmacological selectivity of the… 
Highly Cited
1995
Highly Cited
1995
Electrophysiological properties of P2X‐purinoceptors in rat superior cervical, nodose and guinea‐pig coeliac neurones.
1. Whole‐cell recordings were made from guinea‐pig coeliac, rat nodose and rat superior cervical (SCG) neurones in culture, and… 
Highly Cited
1993
Highly Cited
1993
Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis.
Detrusor specimens were obtained from 5 patients affected by interstitial cystitis (IC) and 5 patients with bladder carcinoma… 
Highly Cited
1979
Highly Cited
1979
Modulation of the evoked release of noradrenaline in canine saphenous vein via presynaptic receptors for adenosine but not ATP.
The effects of adenosine, ATP and adenosine beta, gamma-methylene-5'-triphosphate (APPCP) were compared in the saphenous vein of… 
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