alpha,beta-methyleneadenosine 5'-triphosphate

Known as: 5'-(hydrogen((hydroxy(phosphonooxy)phosphinyl)methyl)phosphonate)adenosine, (.alpha.,.beta.-methylene)adenosine 5'-triphosphate, alpha,beta-methylene ATP 
 
National Institutes of Health

Related topics

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4 relations

Broader (2)

Adenosine TriphosphateAntineoplastic Agents

Narrower (1)

alpha,beta-methyleneadenosine 5'-triphosphate, lithium salt
analogs & derivatives

Papers overview

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Highly Cited
2007
Highly Cited
2007
Structural basis for substrate loading in bacterial RNA polymerase
The mechanism of substrate loading in multisubunit RNA polymerase is crucial for understanding the general principles of… (More)
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Highly Cited
2005
Highly Cited
2005
Metabotropic P2 receptor activation regulates oligodendrocyte progenitor migration and development.
To gain insights into the role of purinergic receptors in oligodendrocyte development, we characterized the expression and… (More)
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Highly Cited
2002
Highly Cited
2002
Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.
Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of diseases with excess… (More)
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2000
2000
Guinea-pig sympathetic neurons express varying proportions of two distinct P2X receptors.
1. Characterization of P2X receptors on neurons of guinea-pig superior cervical ganglion (SCG) has been carried out using a whole… (More)
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Highly Cited
1999
Highly Cited
1999
Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs.
Recently, advances have been made in understanding the molecular mechanisms by which bisphosphonate drugs inhibit bone resorption… (More)
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Highly Cited
1998
Highly Cited
1998
Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets.
ADP is an important platelet agonist causing shape change from smooth discoid shape to spiculated spheres and platelet… (More)
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Highly Cited
1997
Highly Cited
1997
Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat.
1. Intracellular recordings were made in a pontine slice preparation of the rat brain containing the nucleus locus coeruleus (LC… (More)
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Highly Cited
1996
Highly Cited
1996
Second messenger cascade specificity and pharmacological selectivity of the human P2Y1-purinoceptor.
1. The coding sequence of the P2Y1-purinoceptor was cloned from a human genomic library. 2. The open reading frame encodes a… (More)
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Highly Cited
1995
Highly Cited
1995
Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate.
1. The human P2U-purinoceptor was stably expressed in 1321N1 human astrocytoma cells and the pharmacological selectivity of the… (More)
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Highly Cited
1993
Highly Cited
1993
Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis.
Detrusor specimens were obtained from 5 patients affected by interstitial cystitis (IC) and 5 patients with bladder carcinoma… (More)
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