alkyne biosynthetic process

Known as: alkyne formation, alkyne anabolism, alkyne biosynthesis 
The chemical reactions and pathways resulting in the formation of an alkyne, any cyclic branched or unbranched hydrocarbon having a carbon-carbon… (More)
National Institutes of Health

Papers overview

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2014
2014
Chemoresistance of cisplatin therapy is related to extensive repair of cisplatin-modified DNA in the nucleus by the nucleotide… (More)
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Highly Cited
2012
Highly Cited
2012
The endeavour to perform tailored chemical reactions in the challenging environment of the intact cell delves deeply into the… (More)
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Highly Cited
2012
Highly Cited
2012
The copper-catalyzed azide–alkyne cycloaddition, or CuAAC, has been used extensively for the conjugation, immobilization, and… (More)
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2012
2012
The 1,3-dipolar cycloaddition of azides with ring-strained alkynes is one of the few bioorthogonal reactions suitable for… (More)
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2011
Highly Cited
2011
Reactive oxygen species (ROS), such as hydrogen peroxide, are important products of oxygen metabolism that, when misregulated… (More)
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Highly Cited
2011
Highly Cited
2011
The ability to visualize biomolecules within living specimen by engineered fluorescence tags has become a major tool in modern… (More)
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2010
Highly Cited
2010
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, optimized for biological molecules in aqueous buffers, has been… (More)
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2009
Highly Cited
2009
There is considerable interest in the use of bioorthogonal covalent chemistry, such as “click” reactions, to label small… (More)
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2007
2007
The cell adhesion molecule integrin alpha vbeta 3 plays a key role in tumor angiogenesis and metastasis. A series of (18)F… (More)
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Highly Cited
2005
Highly Cited
2005
Covalent bond formation to proteins is made difficult by their multiple unprotected functional groups and normally low… (More)
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