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alkylbase DNA N-glycosylase activity

Known as: alkylbase DNA glycosidase activity, DNA-3-methyladenine glycosidase II activity, DNA-3-methyladenine glycosylase II 
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Entrectinib, a potent oral inhibitor of the tyrosine kinases TRKA/B/C, ROS1, and ALK, was evaluated in two phase I studies in… Expand
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Highly Cited
2013
Highly Cited
2013
BackgroundCyanobacteria can utilize solar energy and convert carbon dioxide into biofuel molecules in one single biological… Expand
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Highly Cited
2004
Highly Cited
2004
DNA damage may be associated with type 2 diabetes mellitus (T2DM) and its complications mainly through oxidative stress. Little… Expand
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Highly Cited
2001
Highly Cited
2001
The enzyme 3-methyladenine DNA glycosylase II (AlkA) is a bacterial repair enzyme that acts preferentially at 3-methyladenine… Expand
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Highly Cited
2000
Highly Cited
2000
The Escherichia coli AlkA protein is a base excision repair glycosylase that removes a variety of alkylated bases from DNA. The 2… Expand
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Highly Cited
1997
Highly Cited
1997
Plasmids were constructed in which DNA damage-inducible promoters recA, uvrA, and alkA from Escherichia coli were fused to the… Expand
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Highly Cited
1997
Highly Cited
1997
The effects of lamb age and diet on volatiles from fat are described. Rendered fat from ram lambs raised on ewe's milk then a… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Reactive oxygen species, ionizing radiation, and other free radical generators initiate the conversion of guanine (G… Expand
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Highly Cited
1994
Highly Cited
1994
The deamination of adenine residues in DNA generates hypoxanthine, which is mutagenic since it gives rise to an A.T to G.C… Expand
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Highly Cited
1949
Highly Cited
1949
I N THE course of experiments on the physiological action of the venom of Bothrope jararaca, we found that some blood samples… Expand
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