alkylbase DNA N-glycosylase activity

Known as: alkylbase DNA glycosidase activity, DNA-3-methyladenine glycosidase II activity, DNA-3-methyladenine glycosylase II 
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2017
010203019502016

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Cyanobacteria can utilize solar energy and convert carbon dioxide into biofuel molecules in one single biological… (More)
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Highly Cited
2004
Highly Cited
2004
DNA damage may be associated with type 2 diabetes mellitus (T2DM) and its complications mainly through oxidative stress. Little… (More)
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2004
2004
Impaired DNA repair may fuel up malignant transformation of breast cells due to the accumulation of spontaneous mutations in… (More)
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Highly Cited
2000
Highly Cited
2000
The Escherichia coli AlkA protein is a base excision repair glycosylase that removes a variety of alkylated bases from DNA. The 2… (More)
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1997
1997
Plasmids were constructed in which DNA damage-inducible promoters recA, uvrA, and alkA from Escherichia coli were fused to the… (More)
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1997
1997
The effects of lamb age and diet on volatiles from fat are described. Rendered fat from ram lambs raised on ewe's milk then a… (More)
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1996
1996
Base-excision DNA repair proteins that target alkylation damage act on a variety of seemingly dissimilar adducts, yet fail to… (More)
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1995
1995
The human carcinogen vinyl chloride is metabolized in the liver to reactive intermediates which generate various ethenobases in… (More)
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Highly Cited
1994
Highly Cited
1994
The deamination of adenine residues in DNA generates hypoxanthine, which is mutagenic since it gives rise to an A.T to G.C… (More)
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1993
1993
Escherichia coli has two DNA glycosylases for repair of DNA damage caused by simple alkylating agents. The inducible AlkA DNA… (More)
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