alditol:NADP+ 1-oxidoreductase activity
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The effects of ursolic acid on the polyol pathway and glucose homeostasis-related metabolism were examined in the livers of… Expand Evidence that Escherichia coli YqhD is involved in bacterial response to compounds that generate membrane lipid peroxidation is… Expand Purpose Activation of polyol pathway due to increased aldose reductase (ALR2) activity has been implicated in the development of… Expand Ginger (Zingiber officinale Roscoe) continues to be used as an important cooking spice and herbal medicine around the world… Expand We tested the hypothesis that the apoptosis of inner retina neurons and increased expression of glial fibrillary acidic protein… Expand Renal medullary cells are naturally exposed to extremely high and variable interstitial concentrations of NaCl and urea… Expand OBJECTIVE
Diabetic hyperglycemia promotes sorbitol production from glucose via aldose reductase. Since the intracellular… Expand Increased sorbitol levels have been demonstrated in tissues of diabetic patients. Although tissue sorbitol levels correlate with… Expand GRB-PAP1 is a continuous line of epithelial cells derived from rabbit renal inner medulla. These cells accumulate large amounts… Expand Although enhanced activity of the polyol pathway has been implicated in the pathogenesis of certain complications of diabetes… Expand