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agouti protein

Known as: Agouti Signaling Protein [Chemical/Ingredient], Agouti Switch Protein, ASIP Protein 
A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in… Expand
National Institutes of Health

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11 relations
ASIP geneIn BloodProcess of secretionagonists
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ASIP protein, humannonagouti protein, mouse

Papers overview

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2010
2010
Pineal-specific agouti protein regulates teleost background adaptation
Background adaptation is used by teleosts as one of a variety of camouflage mechanisms for avoidance of predation. Background… Expand
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Review
2002
Review
2002
Agouti: from mouse to man, from skin to fat.
The agouti protein regulates pigmentation in the mouse hair follicle producing a black hair with a subapical yellow band. Its… Expand
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Highly Cited
2001
Highly Cited
2001
A biochemical function for attractin in agouti-induced pigmentation and obesity
Agouti protein, a paracrine signaling molecule normally limited to skin, is ectopically expressed in lethal yellow (Ay) mice, and… Expand
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Highly Cited
2000
Highly Cited
2000
Role of intracellular calcium in human adipocyte differentiation.
Intracellular calcium ([Ca(2+)](i)) modulates adipocyte lipid metabolism and inhibits the early stages of murine adipogenesis… Expand
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Highly Cited
1997
Highly Cited
1997
Effects of recombinant agouti-signaling protein on melanocortin action.
Mouse agouti protein is a paracrine signaling molecule that has previously been demonstrated to be an antagonist of melanocortin… Expand
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Highly Cited
1996
Highly Cited
1996
Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity.
Mutations leading to ectopic expression of the murine agouti gene (a) result in progressive obesity. To further characterize this… Expand
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Highly Cited
1995
Highly Cited
1995
Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.
Mice that carry the lethal yellow (Ay) or viable yellow (Avy) mutation, two dominant mutations of the agouti (a) gene in mouse… Expand
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Highly Cited
1994
Highly Cited
1994
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
THE genetic loci agouti and extension control the relative amounts of eumelanin (brown–black) and phaeomelanin (yellow–red… Expand
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Highly Cited
1994
Highly Cited
1994
Neomorphic agouti mutations in obese yellow mice
Several dominant mutations of the mouse agouti coat colour gene have pleiotropic effects that include obesity and a yellow coat… Expand
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1953
1953
Total sex-linkage in the house mouse
  • D. S. Falconer
  • Zeitschrift für Induktive Abstammungs- und…
  • 1953
    • Corpus ID: 21148718
Summary1. A totally sex-linked gene, Tabby (Ta), in the house mouse is described. It is semi-dominant in females. Mutant males… Expand
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