FAQ

agouti protein

Known as: Agouti Signaling Protein [Chemical/Ingredient], Agouti Switch Protein, ASIP Protein 
A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
0519752017

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9 relations
ASIP geneIn BloodProcess of secretionagonists
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
agouti protein
physiological aspects
In Blood
chemical synthesis
standards characteristics
Process of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Pineal-specific agouti protein regulates teleost background adaptation.
Background adaptation is used by teleosts as one of a variety of camouflage mechanisms for avoidance of predation. Background… (More)
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2001
2001
Overexpression of agouti protein and stress responsiveness in mice.
Ectopic overexpression of agouti protein, an endogenous antagonist of melanocortin receptors' linked to the beta-actin promoter… (More)
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1998
1998
Melanocortin receptor binding determinants in the agouti protein.
The agouti protein plays an important role in the development of diabetes and obesity in rodents and has been shown to be a… (More)
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1997
1997
Effects of recombinant agouti-signaling protein on melanocortin action.
Mouse agouti protein is a paracrine signaling molecule that has previously been demonstrated to be an antagonist of melanocortin… (More)
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1997
1997
Mutations in the carboxyl terminus of the agouti protein decrease agouti inhibition of ligand binding to the melanocortin receptors.
Several mutations that cause ectopic expression of the agouti gene result in obesity, hyperinsulinemia, and yellow coat color. A… (More)
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Highly Cited
1996
Highly Cited
1996
Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity.
Mutations leading to ectopic expression of the murine agouti gene (a) result in progressive obesity. To further characterize this… (More)
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1996
1996
Coupled site-directed mutagenesis/transgenesis identifies important functional domains of the mouse agouti protein.
The agouti locus encodes a novel paracrine signaling molecule containing a signal sequence, an N-linked glycosylation site, a… (More)
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Highly Cited
1995
Highly Cited
1995
Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.
Mice that carry the lethal yellow (Ay) or viable yellow (Avy) mutation, two dominant mutations of the agouti (a) gene in mouse… (More)
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1995
1995
A transgenic mouse assay for agouti protein activity.
The mouse agouti gene encodes an 131 amino acid paracrine signaling molecule that instructs hair follicle melanocytes to switch… (More)
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Highly Cited
1994
Highly Cited
1994
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
THE genetic loci agouti and extension control the relative amounts of eumelanin (brown–black) and phaeomelanin (yellow–red… (More)
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