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aggrephagy

Selective degradation of protein aggregates by macroautophagy. [GOC:autophagy, GOC:kmv, PMID:18508269, PMID:25062811]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition
Aggrephagy, the aggresome-related protein degradation system, represents a protective cellular response to shuttle misfolded… 
2019
2019
Assays to Monitor Aggrephagy in Drosophila Brain.
Accumulation of ubiquitinated protein aggregates is a hallmark of most aging-related neurodegenerative disorders. Autophagy has… 
2018
2018
Mechanisms of Aggresome Biogenesis Ubiquitination, Transport, & Maintenance
Neurodegenerative diseases are universally marked by the accumulation of misfolded protein. Neurons respond to these proteostatic… 
2018
2018
Abstract 1332: Autophagic clearance of protein aggregates is impaired in cancer cells with dysfunctional mitochondria
Mitophagy and aggrephagy are selective types of autophagy that degrade damaged mitochondria and protein aggregates, respectively… 
2018
2018
Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy
WD repeat and FYVE domain-containing 3 (WDFY3; also known as Autophagy-Linked FYVE or Alfy) is an identified intellectual… 
Review
2017
Review
2017
Kinetics of Protein Aggregates Disposal by Aggrephagy.
2017
2017
HUNTINGTON’S DISEASE: GENETIC MODIFIERS OF AGE AT ONSET AND PATHOLOGICAL BIOMARKERS
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease, clinically characterized by movement disorders… 
2016
2016
Small differences make a big impact: Structural insights into the differential function of the 2 Atg8 homologs in C. elegans
Abstract The 2 C. elegans homologs of Atg8, LGG-1 and LGG-2, show differential function in the degradation of protein aggregates… 
2012
2012
Differential function of the two Atg 4 homologues in the aggrephagy pathway in C . elegans
Fan Wu, Yuping Li, Fuxin Wang, Nobuo N. Noda and Hong Zhang Graduate Program in Chinese Academy of Medical Sciences and Peking… 
2012
2012
Cigarette Smoke Induced Autophagy In The Airway Epithelium Promotes Aggrephagy And Ciliaphagy In Models Of Chronic Obstructive Pulmonary Disease
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