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aflatoxin biosynthetic process

Known as: aflatoxin synthesis, aflatoxin biosynthesis, aflatoxin anabolism 
The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces… Expand
National Institutes of Health

Related topics

Related topics

2 relations
negative regulation of aflatoxin biosynthetic processpositive regulation of aflatoxin biosynthetic process

Papers overview

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Highly Cited
2005
Highly Cited
2005
Sequence breakpoints in the aflatoxin biosynthesis gene cluster and flanking regions in nonaflatoxigenic Aspergillus flavus isolates.
Aspergillus flavus populations are genetically diverse. Isolates that produce either, neither, or both aflatoxins and… Expand
Review
2004
Review
2004
Clustered Pathway Genes in Aflatoxin Biosynthesis
Aflatoxins, a group of polyketide-derived furanocoumarins (Fig. [1][1]), are the most toxic and carcinogenic compounds among the… Expand
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Highly Cited
2004
Highly Cited
2004
veA Is Required for Toxin and Sclerotial Production in Aspergillus parasiticus
ABSTRACT It was long been noted that secondary metabolism is associated with fungal development. In Aspergillus nidulans… Expand
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Highly Cited
2000
Highly Cited
2000
The phylogenetics of mycotoxin and sclerotium production in Aspergillus flavus and Aspergillus oryzae.
Aspergillus flavus is a common filamentous fungus that produces aflatoxins and presents a major threat to agriculture and human… Expand
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Highly Cited
1998
Highly Cited
1998
Genetics and physiology of aflatoxin biosynthesis.
Aflatoxins are the most thoroughly studied mycotoxins. Elegant early research on the biosynthetic scheme of the pathway has… Expand
Highly Cited
1995
Highly Cited
1995
Comparative mapping of aflatoxin pathway gene clusters in Aspergillus parasiticus and Aspergillus flavus.
Aflatoxins are toxic and carcinogenic secondary metabolites produced by the fungi Aspergillus flavus and A. parasiticus… Expand
Highly Cited
1995
Highly Cited
1995
Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis.
The aflR gene from Aspergillus parasiticus and Aspergillus flavus may be involved in the regulation of aflatoxin biosynthesis… Expand
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Highly Cited
1994
Highly Cited
1994
Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis.
Aflatoxins belong to a family of decaketides that are produced as secondary metabolites by Aspergillus flavus and A. parasiticus… Expand
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Highly Cited
1993
Highly Cited
1993
Cloning of the Aspergillus parasiticus apa-2 gene associated with the regulation of aflatoxin biosynthesis.
An Aspergillus parasiticus gene, designated apa-2, was identified as a regulatory gene associated with aflatoxin biosynthesis… Expand
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Highly Cited
1993
Highly Cited
1993
Cloning of the afl-2 gene involved in aflatoxin biosynthesis from Aspergillus flavus.
Aflatoxins are extremely potent carcinogens produced by Aspergillus flavus and Aspergillus parasiticus. Cloning of genes in the… Expand
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