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ado-trastuzumab emtansine 160 MG Injection [KADCYLA]
Known as:
ADO-TRASTUZUMAB EMTANSINE 20 mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [KADCYLA]
, KADCYLA 160 MG Injection
National Institutes of Health
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8 relations
Injection
KADCYLA
Polysorbate 20
Sodium Hydroxide
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
ADCs on the Market and in Clinical Development
Abe Yuki
,
K. Sugihara
,
+4 authors
T. Agatsuma
Cancer Drug Delivery Systems Based on the Tumor…
2019
Corpus ID: 214195507
Antibody–drug conjugates (ADCs) represent a promising class of drugs with a wider therapeutic index (TI) than conventional…
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2017
2017
Enzyme-Based Strategies to Generate Site-Specifically Conjugated Antibody Drug Conjugates
R. Beerli
,
U. Grawunder
2017
Corpus ID: 168672031
Antibody Drug Conjugates (ADCs) exploit the specificity of monoclonal antibodies for the targeting of highly potent small…
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2017
2017
A Mechanism-Based PK/PD Model for Hematological Toxicities Induced by Antibody-Drug Conjugates
S. Ait-Oudhia
,
Weiyan Zhang
,
D. Mager
AAPS Journal
2017
Corpus ID: 255563070
Antibody-drug conjugates (ADCs) are complex drug platforms composed of monoclonal antibodies (mAbs) conjugated to potent…
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Review
2016
Review
2016
Antibody–drug conjugates for targeted anticancer drug delivery
Yejin Kim
,
Eun Ji Park
,
D. Na
Journal of Pharmaceutical Investigation
2016
Corpus ID: 256310307
Antibody–drug conjugates (ADCs) are tumor-targeted therapeutic agents that combine the specificity of monoclonal antibodies (mAbs…
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2015
2015
Abstract 5360: The preclinical profile of the duocarmycin-based HER2-targeting ADC SYD985 predicts for clinical benefit in low HER2-expressing breast cancers
Wim H A Dokter
,
M. Lee
,
+13 authors
M. Timmers
2015
Corpus ID: 73945657
SYD985 is a HER2-targeting ADC based on trastuzumab and vc-seco-DUBA, Synthon9s proprietary cleavable linker-duocarmycin payload…
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Review
2015
Review
2015
Pertuzumab et T-DM1 : de nouvelles perspectives dans le traitement du cancer du sein HER2 positif
S. Guiu
,
P. Fumoleau
,
Lavoisier Sas
ONCOLOGIE
2015
Corpus ID: 34487397
RésuméLe trastuzumab (Herceptine®, Roche) a complètement révolutionné le pronostic du cancer du sein HER2 positif, que ce soit en…
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2015
2015
Употреба на Herceptin® (трастузумаб) и неговиот конјугат Kadcyla® (трастузумаб-емтанзин) во терапија на рак на дојка
M. Sterjova
,
Paulina Apostolova
,
Emilija Janevik-Ivanovska
2015
Corpus ID: 163137950
Трастузумабот е првото одобрено хуманизирано моноклонално антитело, кое е активно против HER2/neu позитивен рак на дојка. HER2…
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2015
2015
Abstract 3601: Antibody-drug conjugates (ADCs) with tubulysin and PBD warheads, maintain potent in vitro cytotoxicity against multidrug-resistant tumor cells expressing P-glycoprotein (P-gp)
S. Mao
,
R. Fleming
,
+8 authors
Jay Harper
2015
Corpus ID: 74122078
Development of resistance to initially-effective therapies remains a major challenge in the treatment of cancer. Resistance to…
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2014
2014
Human antibody phage technology - isolation and characterization of monoclonal antibodies for the targeting of cancer and rheumatoid arthritis
Alessia Putelli
2014
Corpus ID: 70649807
Review
2013
Review
2013
Trastuzumab emtansine (Kadcyla™) for previously treated patients with HER2-positive advanced/metastatic breast cancer
A. Nachtnebel
,
M. Polkowska
,
J. Czeczot
,
R. Joppi
,
C. Poggiani
2013
Corpus ID: 68142464
Trastuzumab emtansine (T-DM1) is currently not yet licensed in Europe, but has received market authorisation in the U.S. based on…
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