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adenylyl cyclase type V

Known as: AC5 enzyme, adenylyl cyclase type 5 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2015
01220002015

Related topics

Related topics

1 relation

Broader (1)

Adenylate Cyclase

Related mentions per year

Related mentions per year

1938-2018
19401960198020002020
adenylyl cyclase type V
Adenylate Cyclase

Papers overview

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2015
2015
Overexpression of adenylyl cyclase type 5 (AC5) confers a proarrhythmic substrate to the heart.
Inhibition of β-adrenergic receptor (β-AR) signaling is one of the most common therapeutic approaches for patients with… (More)
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2014
2014
‘Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption’
Disruption of adenylyl cyclase type 5 (AC5) knockout (KO) is a novel model for longevity. Because malignancy is a major cause of… (More)
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2013
2013
Similarly Potent Inhibition of Adenylyl Cyclase by P-Site Inhibitors in Hearts from Wild Type and AC5 Knockout Mice
Adenylyl cyclase type 5 (AC5) was described as major cardiac AC isoform. The knockout of AC5 (AC5KO) exerted cardioprotective… (More)
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2010
2010
Mice lacking adenylyl cyclase type 5 (AC5) show increased ethanol consumption and reduced ethanol sensitivity
The adenylyl cyclase (AC)/cAMP system is believed to be a key component in regulating alcohol-drinking behavior. It was reported… (More)
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2006
2006
Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action.
Opioid drugs produce their pharmacological effects by activating inhibitory guanine nucleotide-binding regulatory protein-linked… (More)
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2006
2006
Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors.
Signaling and desensitization of G protein-coupled receptor are intimately related, and measuring them separately requires… (More)
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2005
2005
Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to β–adrenergic stimulation
We tested the hypothesis that deletion of adenylyl cyclase type V (ACV) would be associated with decreased left ventricular (LV… (More)
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2002
2002
A critical interplay between Ca2+ inhibition and activation by Mg2+ of AC5 revealed by mutants and chimeric constructs.
Adenylyl cyclase type 5 (AC5) is sensitive to both high and low affinity inhibition by Ca(2+). This property provides a sensitive… (More)
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2000
2000
Ca(2+), Sr(2+), and Ba(2+) identify distinct regulatory sites on adenylyl cyclase (AC) types VI and VIII and consolidate the apposition of capacitative cation entry channels and Ca(2+)-sensitive ACs.
Ca(2+)-sensitive adenylyl cyclases may act as early integrators of the two major second messenger-signaling pathways mediated by… (More)
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2000
2000
Ca, Sr, and Ba Identify Distinct Regulatory Sites on Adenylyl Cyclase (AC) Types VI and VIII and Consolidate the Apposition of Capacitative Cation Entry Channels and Ca-sensitive ACs*
Ca-sensitive adenylyl cyclases may act as early integrators of the two major second messenger-signaling pathways mediated by Ca… (More)
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