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adenylyl cyclase type V
Known as:
AC5 enzyme
, adenylyl cyclase type 5
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Adenylate Cyclase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
A Food and Drug Administration–Approved Antiviral Agent that Inhibits Adenylyl Cyclase Type 5 Protects the Ischemic Heart Even When Administered after Reperfusion
Claudio A Bravo
,
D. Vatner
,
R. Pachon
,
Jie Zhang
,
S. Vatner
The Journal of Pharmacology and Experimental…
2016
Corpus ID: 7442674
A Food and Drug Administration–approved antiviral agent, known as vidarabine or adenine 9-β-D-arabinofuranoside (AraA), has…
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2015
2015
Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling
Keqiang Xie
,
I. Masuho
,
+10 authors
K. Martemyanov
eLife
2015
Corpus ID: 16772988
In the striatum, signaling via G protein-coupled neurotransmitter receptors is essential for motor control. Critical to this…
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2015
2015
Overexpression of adenylyl cyclase type 5 (AC5) confers a proarrhythmic substrate to the heart.
Zhenghang Zhao
,
G. Babu
,
+7 authors
Lai-Hua Xie
American journal of physiology. Heart and…
2015
Corpus ID: 3862753
Inhibition of β-adrenergic receptor (β-AR) signaling is one of the most common therapeutic approaches for patients with…
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Review
2013
Review
2013
Adenylyl cyclase type 5 in cardiac disease, metabolism, and aging.
S. Vatner
,
Misun Park
,
+6 authors
D. Vatner
American journal of physiology. Heart and…
2013
Corpus ID: 20336811
G protein-coupled receptor/adenylyl cyclase (AC)/cAMP signaling is crucial for all cellular responses to physiological and…
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2013
2013
Similarly Potent Inhibition of Adenylyl Cyclase by P-Site Inhibitors in Hearts from Wild Type and AC5 Knockout Mice
Joerg H. Braeunig
,
F. Schweda
,
P. Han
,
R. Seifert
PloS one
2013
Corpus ID: 10099
Adenylyl cyclase type 5 (AC5) was described as major cardiac AC isoform. The knockout of AC5 (AC5KO) exerted cardioprotective…
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2010
2010
Mice lacking adenylyl cyclase type 5 (AC5) show increased ethanol consumption and reduced ethanol sensitivity
Kyoung-Shim Kim
,
Hannah Kim
,
In-Sun Baek
,
Ko-Woon Lee
,
P. Han
Psychopharmacology
2010
Corpus ID: 2500863
RationaleThe adenylyl cyclase (AC)/cAMP system is believed to be a key component in regulating alcohol-drinking behavior. It was…
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Highly Cited
2006
Highly Cited
2006
Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action.
Kyoung-Shim Kim
,
Ko-Woon Lee
,
+6 authors
P. Han
Proceedings of the National Academy of Sciences…
2006
Corpus ID: 27488275
Opioid drugs produce their pharmacological effects by activating inhibitory guanine nucleotide-binding regulatory protein-linked…
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2005
2005
Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to β–adrenergic stimulation
T. Tang
,
N. Lai
,
+6 authors
M. Gao
Basic Research in Cardiology
2005
Corpus ID: 20625011
Abstract We tested the hypothesis that deletion of adenylyl cyclase type V (ACV) would be associated with decreased left…
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2002
2002
A Critical Interplay between Ca2+ Inhibition and Activation by Mg2+ of AC5 Revealed by Mutants and Chimeric Constructs*
Biao Hu
,
H. Nakata
,
C. Gu
,
T. de Beer
,
D. Cooper
The Journal of Biological Chemistry
2002
Corpus ID: 20819266
Adenylyl cyclase type 5 (AC5) is sensitive to both high and low affinity inhibition by Ca2+. This property provides a sensitive…
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2000
2000
Ca2+, Sr2+, and Ba2+ Identify Distinct Regulatory Sites on Adenylyl Cyclase (AC) Types VI and VIII and Consolidate the Apposition of Capacitative Cation Entry Channels and Ca2+-sensitive ACs*
Chenxia Gu
,
D. Cooper
The Journal of Biological Chemistry
2000
Corpus ID: 22276335
Ca2+-sensitive adenylyl cyclases may act as early integrators of the two major second messenger-signaling pathways mediated by…
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