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adenosine triphosphate adenosine monophosphate adenosine monophosphate

Known as: pppA2'p5'A2'p5'A, PPAPAPA, Adenosine 5' -(tetrahydrogen triphosphate), adenylyl-(5'-2')-adenylyl-(5'-2')- 
National Institutes of Health

Related topics

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2 relations

Broader (2)

Adenine NucleotidesOligoribonucleotides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Synthesis and biological activities of a phosphorodithioate analog of 2',5'-oligoadenylate.
To enhance the resistance of 2-5A (pppA2'p5'A2'p5'A) to degradation by exo- and endonucleases, a phosphorodithioate analog was… 
1985
1985
n-Decyl-NHpppA2'p5'A2'p5'A A phosphatase-resistant, active pppA2'p5'A2'p5'A analog.
1985
1985
Sensitive radioimmuno assay for 2',5'-oligoadenylates using a novel 125I-labeled derivative of 2',5'-triadenylate 5'-triphosphate.
A novel 125I-labeled derivative of 2',5'-triadenylate 5'-triphosphate, pppA2'p5'A2'p5'A, with high specific radioactivity was… 
Highly Cited
1979
Highly Cited
1979
An interferon-induced phosphodiesterase degrading (2'-5') oligoisoadenylate and the C-C-A terminus of tRNA.
A phosphodiesterase characterized by a generally higher activity on 2'-5' than on 3'-5' phosphodiester bonds was isolated from… 
Highly Cited
1979
Highly Cited
1979
The (2'-5') oligoadenylate (pppA2'-5'A2'-5'A) synthetase and protein kinase(s) from interferon-treated cells.
Two enzyme activities have been partially purified from interferon-treated mouse L cells: the (2′-5′)An synthetase responsible… 
Highly Cited
1979
Highly Cited
1979
Enzymic synthesis, characterisation and nuclear-magnetic-resonance spectra of pppA2'p5'A2'p5'A and related oligonucleotides: comparison with chemically synthesised material.
We have previously shown that a low-molecular-weight inhibitor (pppA2′p5′A2′p5′A) of cell-free protein synthesis, effective at… 
Highly Cited
1979
Highly Cited
1979
Activation of a nuclease by pppA2′p5′ A2′p5′ A in intact cells
1979
1979
Rapid chemical synthesis and circular dichroism properties of some 2'-5'-linked oligoriboadenylates.
Specific synthesis of some oligoadenylates including A2'p5'A2'p5'Ap(2'), the 2'-phosphorylated oligoribonucleotide core of the… 
Highly Cited
1978
Highly Cited
1978
pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.
  • I. Kerr, R. Brown
  • Proceedings of the National Academy of Sciences…
  • 1978
  • Corpus ID: 22387814
A low molecular weight inhibitor of cell-free protein synthesis effective at subnanomolar concentrations is formed on incubation… 
Highly Cited
1978
Highly Cited
1978
Synthesis and breakdown of pppA2'p5'A2'p5'A and transient inhibiton of protein synthesis in extracts from interferon-treated and control cells.
Incubation of the mouse L-cell-free system with a concentration of pppA2'p5'A2'p5'A [(2'-5')An] just sufficient to inhibit… 
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