acylaminoacyl-peptidase

Known as: EC 3.4.19.1, N-formylmethionine aminopeptidase, Acylamino-Acid-Releasing Enzyme 
Acylamino-acid-releasing enzyme (732 aa, ~81 kDa) is encoded by the human APEH gene. This protein plays a role in aminopeptidase activity.

Topic mentions per year

Topic mentions per year

1976-2017
05101519762017

Papers overview

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2011
2011
Serine hydrolases are a diverse enzyme class representing ∼1% of all human proteins. The biological functions of most serine… (More)
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2008
2008
Amino acid deprivation activates the amino acid response (AAR) pathway that enhances transcription of genes containing an amino… (More)
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2007
2007
The transcriptional activation of CHOP (a CCAAT/enhancer-binding protein-related gene) by amino acid deprivation involves the… (More)
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2007
2007
When an essential amino acid is limited, a signaling cascade is triggered that leads to increased translation of the 'master… (More)
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2007
2007
The adaptive response to amino acid limitation in mammalian cells inhibits global protein synthesis and promotes the expression… (More)
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2007
2007
Expression of ATF3 (activating transcription factor 3) is induced by a variety of environmental stress conditions, including… (More)
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2004
Highly Cited
2004
The CHOP gene is transcriptionally induced by amino acid starvation. We have previously identified a genomic cis-acting element… (More)
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2004
2004
Recent studies have demonstrated that depletion of amino acids results in the induction of several genes and that a genomic cis… (More)
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2004
2004
System A amino acid transporter (SNAT2) gene expression is up-regulated at the transcriptional level in response to amino acid… (More)
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2000
Highly Cited
2000
In mammals, plasma concentration of amino acids is affected by nutritional or pathological conditions. It has been well… (More)
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