acute myeloid leukemia 1 protein

Known as: SL3-3 Enhancer Factor 1 Alpha B Subunit, PEBP2-Alpha B, Pebp2a2 Protein 
A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
To evaluate the prognostic value of genetic mutations for acute myeloid leukemia (AML) patients, we examined the gene status for… (More)
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Review
2008
Review
2008
Myelodysplasia (MDS) and acute myeloid leukemia (AML) are heterogeneous, closely associated diseases arising de novo or following… (More)
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Highly Cited
2003
Highly Cited
2003
1 Shurtleff SA, Buijs A, Behm FG, Rubnitz JE, Raimondi SC, Hancock ML et al. TEL/AML1 fusion resulting from a cryptic t(12;21) is… (More)
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Highly Cited
2002
Highly Cited
2002
The t(8;21) is one of the most frequent chromosomal translocations associated with acute leukemia. This translocation creates a… (More)
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Highly Cited
1999
Highly Cited
1999
Familial platelet disorder with predisposition to acute myelogenous leukaemia (FPD/AML, MIM 601399) is an autosomal dominant… (More)
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Highly Cited
1998
Highly Cited
1998
The t(8;21) translocation between two genes known as AML1 and ETO is seen in approximately 12-15% of all acute myeloid leukemia… (More)
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Highly Cited
1998
Highly Cited
1998
The AML1 transcription factor and the transcriptional coactivators p300 and CBP are the targets of chromosome translocations… (More)
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Highly Cited
1996
Highly Cited
1996
The AML1-CBF beta transcription factor is the most frequent target of chromosomal rearrangements in human leukemia. To… (More)
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Highly Cited
1996
Highly Cited
1996
Polymerase chain reaction-based screening of childhood acute lymphoblastic leukemia (ALL) samples showed that a TEL/AML1 fusion… (More)
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Highly Cited
1995
Highly Cited
1995
Analysis of a growing number of chromosomal translocations in human tumors have shown that they frequently result in gene fusions… (More)
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