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acute myeloid leukemia 1 protein

Known as: SL3-3 Enhancer Factor 1 Alpha B Subunit, PEBP2-Alpha B, Pebp2a2 Protein 
A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
High-throughput DNA sequencing significantly contributed to diagnosis and prognostication in patients with myelodysplastic… Expand
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Highly Cited
2012
Highly Cited
2012
Breast carcinoma is the leading cause of cancer-related mortality in women worldwide, with an estimated 1.38 million new cases… Expand
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Highly Cited
2012
Highly Cited
2012
To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with somatic alterations, we studied… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Myelodysplastic syndromes are clinically heterogeneous disorders characterized by clonal hematopoiesis, impaired… Expand
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Highly Cited
2009
Highly Cited
2009
Haematopoietic stem cells (HSCs) are the founder cells of the adult haematopoietic system, and thus knowledge of the molecular… Expand
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Highly Cited
1999
Highly Cited
1999
Familial platelet disorder with predisposition to acute myelogenous leukaemia (FPD/AML, MIM 601399) is an autosomal dominant… Expand
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Highly Cited
1998
Highly Cited
1998
The t(8;21) translocation between two genes known as AML1 and ETO is seen in approximately 12-15% of all acute myeloid leukemia… Expand
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Highly Cited
1996
Highly Cited
1996
The AML1-CBF beta transcription factor is the most frequent target of chromosomal rearrangements in human leukemia. To… Expand
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Highly Cited
1996
Highly Cited
1996
The CBFA2 (AML1) gene encodes a DNA-binding subunit of the heterodimeric core-binding factor. The CBFA2 gene is disrupted by the… Expand
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Highly Cited
1991
Highly Cited
1991
The t(8;21)(q22;q22) translocation is a non-random chromosomal abnormality frequently found in patients with acute myeloid… Expand
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