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activation of protein kinase A activity

Known as: protein kinase A activation 
Any process that initiates the activity of the inactive enzyme protein kinase A. [GOC:pde]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Knock‐In of the Recurrent R368X Mutation of PRKAR1A that Represses cAMP‐Dependent Protein Kinase A Activation: A Model of Type 1 Acrodysostosis
In humans, activating mutations in the PRKAR1A gene cause acrodysostosis 1 (ACRDYS1). These mutations result in a reduction in… 
Highly Cited
2016
Highly Cited
2016
Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis
Cancer cells often rely on glycolysis to obtain energy and support anabolic growth. Several studies showed that glycolytic cells… 
2015
2015
Escitalopram Ameliorates Tau Hyperphosphorylation and Spatial Memory Deficits Induced by Protein Kinase A Activation in Sprague Dawley Rats.
Here, we investigated the effect of escitalopram pretreatment on protein kinase A (PKA)-induced tau hyperphosphorylation and… 
2014
2014
Protein Kinase A Activation Enhances β-Catenin Transcriptional Activity through Nuclear Localization to PML Bodies
The Protein Kinase A (PKA) and Wnt signaling cascades are fundamental pathways involved in cellular development and maintenance… 
Highly Cited
2013
Highly Cited
2013
β-Cell–Specific Protein Kinase A Activation Enhances the Efficiency of Glucose Control by Increasing Acute-Phase Insulin Secretion
Acute insulin secretion determines the efficiency of glucose clearance. Moreover, impaired acute insulin release is… 
2013
2013
Non-steroidal anti-inflammatory drugs activate NADPH oxidase in adipocytes and raise the H2O2 pool to prevent cAMP-stimulated protein kinase a activation and inhibit lipolysis
BackgroundNon-steroidal anti-inflammatory drugs (NSAIDs) —aspirin, naproxen, nimesulide, and piroxicam— lowered activation of… 
Highly Cited
2010
Highly Cited
2010
Temporal Sensitivity of Protein Kinase A Activation in Late-Phase Long Term Potentiation
Protein kinases play critical roles in learning and memory and in long term potentiation (LTP), a form of synaptic plasticity… 
2009
2009
Protein Kinase A Activation Confers Resistance to Trastuzumab in Human Breast Cancer Cell Lines
Purpose: Trastuzumab is a monoclonal antibody targeted to the Her2 receptor and approved for treatment of Her2-positive breast… 
Highly Cited
2008
Highly Cited
2008
Integrin-mediated protein kinase A activation at the leading edge of migrating cells.
cAMP-dependent protein kinase A (PKA) is important in processes requiring localized cell protrusion, such as cell migration and… 
2001
2001
Protein Kinase A Activation Phosphorylates the Rat ClC-2 Cl− Channel but Does Not Change Activity
Abstract. Phosphorylation-dependent events have been shown to modulate the activity of several members of the mammalian CLC Cl… 
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