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activation of protein kinase A activity
Known as:
protein kinase A activation
Any process that initiates the activity of the inactive enzyme protein kinase A. [GOC:pde]
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Knock‐In of the Recurrent R368X Mutation of PRKAR1A that Represses cAMP‐Dependent Protein Kinase A Activation: A Model of Type 1 Acrodysostosis
C. Le Stunff
,
F. Tilotta
,
+7 authors
C. Silve
Journal of bone and mineral research : the…
2017
Corpus ID: 22544528
In humans, activating mutations in the PRKAR1A gene cause acrodysostosis 1 (ACRDYS1). These mutations result in a reduction in…
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Highly Cited
2016
Highly Cited
2016
Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis
R. Palorini
,
G. Votta
,
+13 authors
F. Chiaradonna
PLoS genetics
2016
Corpus ID: 11723424
Cancer cells often rely on glycolysis to obtain energy and support anabolic growth. Several studies showed that glycolytic cells…
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2015
2015
Escitalopram Ameliorates Tau Hyperphosphorylation and Spatial Memory Deficits Induced by Protein Kinase A Activation in Sprague Dawley Rats.
Qing-Guo Ren
,
Yan-juan Wang
,
W. Gong
,
Lin Xu
,
Zhi-jun Zhang
Journal of Alzheimer's disease : JAD
2015
Corpus ID: 36462743
Here, we investigated the effect of escitalopram pretreatment on protein kinase A (PKA)-induced tau hyperphosphorylation and…
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2014
2014
Protein Kinase A Activation Enhances β-Catenin Transcriptional Activity through Nuclear Localization to PML Bodies
Mei Zhang
,
Emilia Mahoney
,
T. Zuo
,
P. Manchanda
,
R. Davuluri
,
L. Kirschner
PloS one
2014
Corpus ID: 3143882
The Protein Kinase A (PKA) and Wnt signaling cascades are fundamental pathways involved in cellular development and maintenance…
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Highly Cited
2013
Highly Cited
2013
β-Cell–Specific Protein Kinase A Activation Enhances the Efficiency of Glucose Control by Increasing Acute-Phase Insulin Secretion
Kelly Kaihara
,
L. M. Dickson
,
+4 authors
B. Wicksteed
Diabetes
2013
Corpus ID: 15915266
Acute insulin secretion determines the efficiency of glucose clearance. Moreover, impaired acute insulin release is…
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2013
2013
Non-steroidal anti-inflammatory drugs activate NADPH oxidase in adipocytes and raise the H2O2 pool to prevent cAMP-stimulated protein kinase a activation and inhibit lipolysis
H. Vázquez-Meza
,
Martha Zentella de Piña
,
J. P. Pardo
,
H. Riveros-Rosas
,
R. Villalobos-Molina
,
E. Piña
BMC Biochemistry
2013
Corpus ID: 17179503
BackgroundNon-steroidal anti-inflammatory drugs (NSAIDs) —aspirin, naproxen, nimesulide, and piroxicam— lowered activation of…
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Highly Cited
2010
Highly Cited
2010
Temporal Sensitivity of Protein Kinase A Activation in Late-Phase Long Term Potentiation
Myungsook Kim
,
Ted Huang
,
T. Abel
,
K. Blackwell
PLoS Comput. Biol.
2010
Corpus ID: 13480035
Protein kinases play critical roles in learning and memory and in long term potentiation (LTP), a form of synaptic plasticity…
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2009
2009
Protein Kinase A Activation Confers Resistance to Trastuzumab in Human Breast Cancer Cell Lines
Long Gu
,
S. Lau
,
S. Loera
,
G. Somlo
,
S. Kane
Clinical Cancer Research
2009
Corpus ID: 18123752
Purpose: Trastuzumab is a monoclonal antibody targeted to the Her2 receptor and approved for treatment of Her2-positive breast…
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Highly Cited
2008
Highly Cited
2008
Integrin-mediated protein kinase A activation at the leading edge of migrating cells.
C. Lim
,
Kristin H. Kain
,
+6 authors
M. Ginsberg
Molecular biology of the cell
2008
Corpus ID: 10017786
cAMP-dependent protein kinase A (PKA) is important in processes requiring localized cell protrusion, such as cell migration and…
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2001
2001
Protein Kinase A Activation Phosphorylates the Rat ClC-2 Cl− Channel but Does Not Change Activity
K. Park
,
T. Begenisich
,
J. E. Melvin
The Journal of Membrane Biology
2001
Corpus ID: 10076600
Abstract. Phosphorylation-dependent events have been shown to modulate the activity of several members of the mammalian CLC Cl…
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