activation-induced cell death

Known as: AICD 
 
National Institutes of Health

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3 relations
Activation-induced cell death of T cellsactivation-induced B cell apoptotic processmacrophage apoptotic process

Papers overview

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2017
2017
Transmembrane TNF-α promotes activation-induced cell death by forward and reverse signaling
Secretory tumor necrosis factor-alpha (sTNF-α) is known to mediate activation- induced cell death (AICD). However, the role of… Expand
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2017
2017
Soluble TNF-a but not transmembrane TNF-a sensitizes T cells for enhanced activation-induced cell death
In addition to its proinflammatory effects, TNF-a exhibits immunosuppression. Here, we compared the capacities of transmembrane… Expand
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2017
2017
New link between Parkinson's and Alzheimer's: Research uncovers the role of mutant leucine rich repeat kinase 2 and amyloid precursor protein.
Of the known genetic factors contributing to Parkinson’s disease (PD), pathogenic leucine rich repeat kinase 2 (LRRK2) is… Expand
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2014
2014
Activation-induced cell death in T lymphocytes from multiple sclerosis patients
Apoptosis is a major mechanism regulating immune tolerance by the elimination of autoreactive T lymphocytes. A failure of… Expand
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Review
2014
Review
2014
The Intracellular Domain of Amyloid Precursor Protein is a Potential Therapeutic Target in Alzheimer's Disease.
Amyloid-β (Aβ) is widely believed to cause Alzheimer's disease (AD), as it is the major constituent of the amyloid plaques… Expand
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2014
2014
593 Modulation of the F1F0-ATPase Induces Apoptosis of Mouse and Human Lamina Propria T-cells and Is Efficacious in Models of IBD
Background: There is an increasing recognition that targeting immune metabolism may represent a new approach for therapeutic… Expand
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2013
2013
Modeling interleukin-2-based immunotherapy in AIDS pathogenesis.
In this paper, we sought to identify the CD4(+) T-cell dynamics in the course of HIV infection in response to continuous and… Expand
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2008
2008
The intracellular domain of amyloid precursor protein induces neuron-specific apoptosis
Although amyloid precursor protein (APP) has central roles in Alzheimer's disease, the physiological functions of this protein… Expand
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2005
2005
Activation or suppression of NFκB by HPK1 determines sensitivity to activation-induced cell death
Restimulation of the T-cell receptor (TCR) in activated T cells induces CD95 (Fas/Apo-1)-mediated activation-induced cell death… Expand
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Review
2003
Review
2003
T cell apoptosis and reactive oxygen species.
Summary Thousands of studies of ROS and their effects on cellshave been reported. Therefore it is not surprising thatthese… Expand
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