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actinomycin C3

Known as: Aurathin-A3, AY 3, Actinomycin AY1 
A natural analogue of actinomycin, a chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin C3 inhibits… Expand
National Institutes of Health

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Highly Cited
2003
Highly Cited
2003
Abstract Tumor necrosis factor (TNFα) receptor signaling can simultaneously activate caspase 8, the transcription factor, NF-κB… Expand
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Highly Cited
2002
Highly Cited
2002
Mitochondrial outer membrane permeabilization by proapoptotic Bcl-2 family proteins, such as Bax, plays a crucial role in… Expand
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Highly Cited
2001
Highly Cited
2001
Statins are inhibitors of the rate-limiting enzyme in cholesterol synthesis, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA… Expand
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Highly Cited
1997
Highly Cited
1997
Hypoxia induces vasoconstriction, in part, by down-regulating endothelial cell nitric oxide synthase (ecNOS) expression. Previous… Expand
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Highly Cited
1997
Highly Cited
1997
Omentum has been used clinically to promote wound healing and to stimulate the revascularization of ischemic tissues. The… Expand
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Highly Cited
1996
Highly Cited
1996
Curcumin, widely used as a spice and coloring agent in food, possesses potent antioxidant, anti-inflammatory and anti-tumor… Expand
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Highly Cited
1994
Highly Cited
1994
Freshly isolated mouse hepatocytes were essentially insensitive to TNF-alpha cytotoxicity. However, TNF-alpha induced a… Expand
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Highly Cited
1987
Highly Cited
1987
An early event in death of interphase lymphocytes exposed in vivo or in vitro to low doses of gamma-irradiation is the… Expand
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Highly Cited
1982
Highly Cited
1982
A retrovirus (ATLV) was unequivocally demonstrated in human adult T-cell leukemia (ATL) cell lines by density (1.152-1.155 g/cm3… Expand
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Highly Cited
1974
Highly Cited
1974
Based on evidence that 50% of herpes simplex 1 DNA is transcribed in HEp-2 cells in the absence of protein synthesis we examined… Expand
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