actin nucleation

Known as: actin filament nucleation 
The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
Actin polymerization essential for endocytic internalization in budding yeast is controlled by four nucleation promoting factors… (More)
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Highly Cited
2005
Highly Cited
2005
The actin cytoskeleton is essential for many cellular functions including shape determination, intracellular transport and… (More)
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Highly Cited
2002
Highly Cited
2002
Formins are required for cell polarization and cytokinesis, but do not have a defined biochemical activity. In Saccharomyces… (More)
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Highly Cited
2002
Highly Cited
2002
Rac signalling to actin—a pathway that is thought to be mediated by the protein Scar/WAVE (WASP (Wiskott–Aldrich syndrome protein… (More)
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Review
2001
Review
2001
Reorganization of cortical actin filaments plays critical roles in cell movement and pattern formation. Recently, the WASP and… (More)
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Highly Cited
2001
Highly Cited
2001
Rearrangements of the actin cytoskeleton are involved in a variety of cellular processes from locomotion of cells to… (More)
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Highly Cited
2001
Highly Cited
2001
We have performed computer simulations and free energy calculations to determine the thermodynamics and kinetics of actin… (More)
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Highly Cited
1999
Highly Cited
1999
Actin polymerization at the cell cortex is thought to provide the driving force for aspects of cell-shape change and locomotion… (More)
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Highly Cited
1999
Highly Cited
1999
humans (Welch et al., 1997b), and Xenopus laevis (Ma Although small GTP-binding proteins of the Rho family et al., 1998b). The… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The actin-related proteins Arp2 and Arp3 are part of a seven-protein complex which is localized in the lamellipodia of… (More)
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