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actin nucleation

Known as: actin filament nucleation 
The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the… 
National Institutes of Health

Related topics

Related topics

1 relation
negative regulation of actin nucleation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
HSP90 cross‐links branched actin filaments induced by N‐WASP and the Arp2/3 complex
N‐WASP induces filopodial actin cytoskeleton through activation of the Arp2/3 complex. Here, we show that heat shock protein 90… 
2006
2006
ARP2 and ARP3 are localized to sites of actin filament nucleation in tobacco BY-2 cells
Summary.Complete depolymerization of actin filaments (AFs) at low temperature (0 °C) is followed by the formation of transient… 
Highly Cited
2004
Highly Cited
2004
Delineation and characterization of the actin nucleation and effector translocation activities of Salmonella SipC
Salmonella type III secreted SipC possesses dual functions: translocation of effectors and actin modulation. The biological… 
Highly Cited
2003
Highly Cited
2003
Caldesmon Inhibits Arp2/3-mediated Actin Nucleation*
The Arp2/3 complex greatly accelerates actin polymerization, which is thought to play a major role in cell motility by inducing… 
Highly Cited
2001
Highly Cited
2001
Tyrosine Phosphorylation of Villin Regulates the Organization of the Actin Cytoskeleton*
We have previously shown that tyrosine phosphorylation of the actin-regulatory protein villin is accompanied by the… 
Highly Cited
2000
Highly Cited
2000
Specific Requirement for the p85-p110α Phosphatidylinositol 3-Kinase during Epidermal Growth Factor-stimulated Actin Nucleation in Breast Cancer Cells*
We have studied the role of phosphatidylinositol 3-kinases (PI 3-kinases) in the regulation of the actin cytoskeleton in MTLn3… 
1998
1998
Localization by Segmental Deletion Analysis and Functional Characterization of a Third Actin-binding Site in Domain 5 of Scinderin*
Scinderin is a Ca2+-dependent actin filament severing protein present in a variety of secretory cells. Previous work suggests… 
1993
1993
Cellular automaton model of the actin cytoskeleton.
We describe a cellular automaton model of the actin cytoskeleton. The model incorporates spatial and temporal behavior at the… 
1991
1991
Purification and characterization of aginactin, a newly identified agonist-regulated actin-capping protein from Dictyostelium amoebae.
Highly Cited
1988
Highly Cited
1988
Actin polymerization and pseudopod extension during amoeboid chemotaxis.
Amoebae of the cellular slime mold Dictyostelium discoideum are an excellent model system for the study of amoeboid chemotaxis… 
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