aconitate hydratase activity

Known as: aconitase activity, citrate(isocitrate) hydro-lyase (cis-aconitate-forming), citrate(isocitrate) hydro-lyase activity 
Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O… (More)

Topic mentions per year

Topic mentions per year

1953-2018
0102019532017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
NAD(P)H oxidases (Noxs) produce O(2)(-) and play an important role in cardiovascular pathophysiology. The Nox4 isoform is… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
BACKGROUND Hypoxia in cancers results in the upregulation of hypoxia inducible factor 1 (HIF-1) and a microRNA, hsa-miR-210 (miR… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Parkinson's disease (PD) is a common neurodegenerative movement disorder. Whereas the majority of PD cases are sporadic, rare… (More)
  • figure 1
  • figure 3
  • figure 2
  • table 1
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Numerous degenerative disorders are associated with elevated levels of prooxidants and declines in mitochondrial aconitase… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The physiological role of huntingtin and the mechanisms by which the expanded CAG repeat in ITI5 and its polyglutamine stretch in… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The mechanisms that cause aging are not well understood. The oxidative stress hypothesis proposes that the changes associated… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Aconitase is a member of a family of iron-sulfur-containing (de)hydratases whose activities are modulated in bacteria by… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
A system based on Arabidopsis thaliana suspension cultures was established for the analysis of glutathione (GSH) synthesis in the… (More)
Is this relevant?
Highly Cited
1988
Highly Cited
1988
The experiments reported here identify nitric oxide as a molecular effector of activated macrophage induced cytotoxicity… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
L-Arginine is required for expression of the activated macrophage cytotoxic effector mechanism that causes inhibition of… (More)
Is this relevant?