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acetylenecarboxylate hydratase activity, producing 3-oxopropanoate

Known as: acetylmonocarboxylic acid hydrase activity, acetylenecarboxylate hydratase activity, producing malonate-semialdehyde, 3-oxopropanoate hydro-lyase (propynoate-forming) 
Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O. [EC:, MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN]
National Institutes of Health

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We have developed one-pot method for the synthesis of functionalized novel cyclopentadiene-fused chromanone scaffolds. A variety… 
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