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acetylacetoin reductase (NADPH)

Known as: AACR I 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Metastasis to distant tissues is the chief driver of breast cancer-related mortality, but little is known about the systemic… Expand
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Highly Cited
2010
Highly Cited
2010
Resveratrol, a naturally occurring polyphenol, has cancer chemopreventive properties in preclinical models. It has been shown to… Expand
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Highly Cited
2010
Highly Cited
2010
Mutation at the R132 residue of isocitrate dehydrogenase 1 (IDH1), frequently found in gliomas and acute myelogenous leukemia… Expand
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Highly Cited
2010
Highly Cited
2010
Activation of the mammalian target of rapamycin (mTOR) pathway is an important and early event in tobacco carcinogen–induced lung… Expand
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Highly Cited
2010
Highly Cited
2010
Resveratrol is a phytochemical with chemopreventive activity in preclinical rodent models of colorectal carcinogenesis… Expand
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Highly Cited
2010
Highly Cited
2010
Purpose: MicroRNAs (miRNA) are short noncoding RNAs that can play critical roles in diverse biological processes. They are… Expand
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Highly Cited
2010
Highly Cited
2010
The biguanide metformin is widely used for treating diabetes mellitus. We previously showed the chemopreventive effect of… Expand
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Highly Cited
2010
Highly Cited
2010
Purpose: Lung squamous cell carcinoma (SCC) is clinically and genetically heterogeneous, and current diagnostic practices do not… Expand
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Highly Cited
2010
Highly Cited
2010
Mutational activation of KRAS is a common event in human tumors. Identification of the key signaling pathways downstream of… Expand
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Highly Cited
2010
Highly Cited
2010
Targeted therapeutics hold tremendous promise in inhibiting cancer cell proliferation. However, targeting proteins individually… Expand
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