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acetyl-5-aminosalicylic acid

Known as: acetyl-5-ASA 
National Institutes of Health

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Aminosalicylic Acids

Papers overview

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2001
2001
Pharmacological Development of Aminosalicylates for the Treatment of Inflammatory Bowel Disease
Metabolic experiments with labelled SASP, 5-ASA and SP in mice demonstrated that the azo-link was split by bacterial reduction… 
1996
1996
Systemic uptake of 5‐aminosalicylic acid from olsalazine and eudragit L coated mesalazine in patients with ulcerative colitis in remission: 526
UNLABELLED Aminosalicylates are used to maintain remission in patients with ulcerative colitis. Since there are potential… 
1989
1989
5-Aminosalicylic acid concentration in mucosal interstitium of cat small and large intestine
Uncertainty regarding the concentration of 5-ASA within the mucosal interstitium has been a major limitation of defining the… 
1988
1988
Pharmacokinetics of olsalazine and its metabolites.
After a single dose of olsalazine, the maximum serum concentration of the intact compound is much lower than after an equivalent… 
1988
1988
Stability of disodium azodisalicylate (olsalazine) and metabolites in urine and faeces stored at different temperatures
SummaryMethods: The stability of disodium azodisalicylate, 5-aminosalicylic acid and acetyl-5-aminosalicylic acid dissolved in… 
1986
1986
Steady-state kinetics of 5-aminosalicylic acid and sulfapyridine during sulfasalazine prophylaxis in ulcerative colitis.
Fifteen adult and 19 pediatric outpatients with ulcerative colitis were studied to determine the steady-state kinetics of 5…