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acetoacetate

Known as: 3-ketobutyrate, oxobutyrate 
 
National Institutes of Health

Papers overview

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2017
2017
OBJECTIVE The ketogenic diet is clinically used to treat drug-resistant epilepsy. The diet treatment markedly increases ketone… Expand
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Highly Cited
2006
Highly Cited
2006
Glutamate cytotoxicity contributes to neuronal degeneration in many central nervous system (CNS) diseases, such as epilepsy and… Expand
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Highly Cited
2003
Highly Cited
2003
Glucose is the main substrate that fulfills energy brain demands. However, in some circumstances, such as diabetes, starvation… Expand
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Highly Cited
2002
Highly Cited
2002
Low HDL cholesterol is a frequent cardiovascular risk factor in diabetes. Because of its pivotal role for the regulation of HDL… Expand
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1992
1992
The enzyme mercaptopyruvate sulfurtransferase appears to play an important role in the in vivo detoxification of cyanide. It does… Expand
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Highly Cited
1991
Highly Cited
1991
Acetoacetate, when present as the only fuel for respiration in rat hearts, causes an impairment in contractile function that is… Expand
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1986
1986
Primary cultures of astrocytes and neurons derived from neonatal and embryonic mouse cerebral cortex, respectively, were… Expand
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1973
1973
The existence of acetoacetyl-CoA synthetase in rat brain cytosol is reported. The coupling of this enzyme with cytosolic… Expand
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1970
1970
1. Acetoacetate or dl-beta-hydroxybutyrate increases the rate of oxygen consumption to a smaller extent than that brought about… Expand
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1961
1961
Interference with the removal of oxaloacetate through citrate formation would naturally impair the catalytic oxidation of… Expand
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