acetoacetate

Known as: 3-ketobutyrate, oxobutyrate 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2017
051019502016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Fasting has been used to control epilepsy since antiquity, but the mechanism of coupling between metabolic state and excitatory… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Poly(ADP-ribose)-1 (PARP-1) is a key mediator of cell death in excitotoxicity, ischemia, and oxidative stress. PARP-1 activation… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
2006
2006
Glutamate cytotoxicity contributes to neuronal degeneration in many central nervous system (CNS) diseases, such as epilepsy and… (More)
Is this relevant?
2003
2003
Glucose is the main substrate that fulfills energy brain demands. However, in some circumstances, such as diabetes, starvation… (More)
Is this relevant?
2002
2002
Low HDL cholesterol is a frequent cardiovascular risk factor in diabetes. Because of its pivotal role for the regulation of HDL… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
1998
1998
Elevated level of cellular lipid peroxidation can increase the incidence of vascular disease. The mechanism by which ketosis… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Acetoacetate, when present as the only fuel for respiration in rat hearts, causes an impairment in contractile function that is… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
To determine the temporal relationship between changes in contractile performance and flux through the citric acid cycle in… (More)
  • table I
  • table I
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Maximum activities of some key enzymes of metabolism were studied in elicited (inflammatory) macrophages of the mouse and lymph… (More)
Is this relevant?
1970
1970
1. Acetoacetate or dl-beta-hydroxybutyrate increases the rate of oxygen consumption to a smaller extent than that brought about… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?