acadesine

Known as: AICA-riboside, 5-Amino-4-imidazolecarboxamide Ribofuranoside, 1-ribosyl-4-carboxamido-5-aminoimidazole 
A 5-aminoimidazole-4-carboxamide (AICA) riboside, a ribnucleoside analog, and a nucleotide biosynthesis precursor with B cell pro-apoptotic activity… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Autophagy, a lysosome-mediated catabolic process, contributes to maintenance of intracellular homeostasis and cellular response… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Metformin is an antidiabetic drug commonly used to treat type 2 diabetes. The aim of the study was to determine whether… (More)
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Highly Cited
2007
Highly Cited
2007
Resveratrol is a polyphenol produced by plants that has multiple beneficial activities similar to those associated with caloric… (More)
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Highly Cited
2005
Highly Cited
2005
Recent studies indicate that the LKB1 tumour suppressor protein kinase is the major "upstream" activator of the energy sensor AMP… (More)
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Review
2005
Review
2005
Exercise/muscle contraction activates glucose transport. The increase in muscle glucose transport induced by exercise is… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The AMP-activated protein kinase (AMPK) cascade is a sensor of cellular energy charge that acts as a 'metabolic master… (More)
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Highly Cited
2003
Highly Cited
2003
Contraction of rat cardiac myocytes induces translocation of fatty acid translocase (FAT)/CD36 and GLUT4 from intracellular… (More)
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Highly Cited
2002
Highly Cited
2002
Protein synthesis, in particular peptide-chain elongation, consumes cellular energy. Anoxia activates AMP-activated protein… (More)
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Highly Cited
2000
Highly Cited
2000
Muscle contraction causes an increase in activity of 5'-AMP-activated protein kinase (AMPK). This study was designed to determine… (More)
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Highly Cited
1999
Highly Cited
1999
Insulin increases glucose uptake through the translocation of GLUT-4 via a pathway mediated by phosphatidylinositol 3-kinase… (More)
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