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Zinc Finger Protein PLAG1

Known as: PLAG1, Pleiomorphic Adenoma Gene 1 Protein 
Zinc finger protein PLAG1 (500 aa, ~56 kDa) is encoded by the human PLAG1 gene. This protein is a C2H2-type zinc finger transcription factor that… 
National Institutes of Health

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CYS2-HIS2 Zinc FingersDNA-Binding ProteinsGenes, RegulatorPLAG1 gene

Papers overview

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Highly Cited
2018
Highly Cited
2018
The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer.
Highly Cited
2016
Highly Cited
2016
Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants
Whole-genome sequencing data allow detection of copy number variation (CNV) at high resolution. However, estimation based on read… 
Highly Cited
2008
Highly Cited
2008
High-resolution array CGH analysis of salivary gland tumors reveals fusion and amplification of the FGFR1 and PLAG1 genes in ring chromosomes
We have previously identified a subgroup of pleomorphic salivary gland adenomas with ring chromosomes of uncertain derivation… 
Highly Cited
2006
Highly Cited
2006
CHCHD7‐PLAG1 and TCEA1‐PLAG1 gene fusions resulting from cryptic, intrachromosomal 8q rearrangements in pleomorphic salivary gland adenomas
Pleomorphic salivary gland adenomas are characterized by recurrent chromosome rearrangements of 8q12, leading to activation of… 
Highly Cited
2004
Highly Cited
2004
Amplification and overexpression of the IGF2 regulator PLAG1 in hepatoblastoma
There is evidence that 8q amplification is associated with poor prognosis in hepatoblastoma. A previous comparative genomic… 
Highly Cited
2000
Highly Cited
2000
PLAG1 fusion oncogenes in lipoblastoma.
Lipoblastomas are pediatric neoplasms resulting from transformation of adipocytes. These benign tumors are typically composed of… 
Highly Cited
2000
Highly Cited
2000
PLAG1, the main translocation target in pleomorphic adenoma of the salivary glands, is a positive regulator of IGF-II.
PLAG1, a novel developmentally regulated C2H2 zinc finger gene, is consistently rearranged and overexpressed in pleomorphic… 
Review
1999
Review
1999
Fusion genes in solid tumors.
Tumor development in different cell types and tissue locations involves many pathways, distinct genes and exogenous factors… 
Highly Cited
1998
Highly Cited
1998
Transcriptional Activation Capacity of the Novel PLAG Family of Zinc Finger Proteins*
We have isolated and characterized two novel cDNAs encoding C2H2 zinc finger proteins showing high sequence homology to PLAG1, a… 
Highly Cited
1997
Highly Cited
1997
Promoter swapping between the genes for a novel zinc finger protein and β-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations
Pleiomorphic adenoma of the salivary glands is a benign epithelial tumour occurring primarily in the major and minor salivary… 
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