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Disturbances of the limbic-hypothalamic-pituitary-adrenal axis and the serotonin system are commonly found in… Expand There are conflicting results on the function of 5-HT in anxiety and depression. To reconcile this evidence, Deakin and Graeff… Expand The etiology and optimum treatment of panic disorder remain unclear. Imipramine and alprazolam are reasonably well established… Expand The amygdala (AM) and the periaqueductal gray (PAG) represent the rostral and the caudal pole, respectively, of a longitudinally… Expand The clinical pharmacology, adverse event profiles, and clinical efficacy of several serotonin reuptake inhibitors are summarized… Expand Reports of the antiobsessional efficacy of clomipramine have led to a "serotonin hypothesis" of obsessive-compulsive disorder… Expand The effect of zimelidine, a specific serotonin‐reuptake inhibitor, on alcohol intake was tested in 13 healthy male, nondepressed… Expand Zimelidine, a selective serotonergic (5HT) reuptake blocker, is a clinically effective antidepressant. However, its rapid action… Expand Radioligand receptor binding techniques were used to characterize the effects of different structural types of antidepressant… Expand The present experiments were undertaken to ascertain whether non-tricyclic, clinically effective, antidepressant drugs such as… Expand