ZOFENOPRIL CALCIUM

The calcium salt of zofenopril, a sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, zofenopril… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
01219892017

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2014
2014
AIMS Therapeutic use of sulfhydrylated inhibitor S-zofenopril has raised different hypotheses regarding the role played by its… (More)
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2007
2007
Angiotensin-converting enzyme inhibitors (ACEIs) and calcium antagonists are today extensively used as first-line monotherapy as… (More)
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2004
2004
(4S)-1-[(S)-3-Mercapto-2-methylpropanoyl]-4-phenylthio-L-proline (Zofenoprilat, 2), the active metabolite of the potent ACE… (More)
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2000
2000
Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound zofenoprilat… (More)
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Review
1999
Review
1999
The discovery of captopril, the prototype of orally active angiotensin-converting enzyme inhibitors (ACEIs), represented a major… (More)
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1994
1994
Comparative in vitro dissolution studies were performed on several tablet batches of zofenopril calcium, an ACE inhibitor, to… (More)
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1993
1993
Angiotensin-converting enzyme (ACE) inhibitors have been designed to block the renin-angiotensin system and can represent an… (More)
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1991
1991
The relative contribution of the gut, liver, and lungs as sites of first-pass bioactivation (hydrolysis) of the orally… (More)
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1990
1990
Zofenopril calcium (1) is a prodrug that is hydrolyzed in vivo to the active angiotensin-converting enzyme (ACE) inhibitor SQ 26… (More)
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1989
1989
Zofenopril calcium (one-half calcium salt) is a prodrug ester analog of captopril whose biological effects are manifested by its… (More)
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