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ZOFENOPRIL CALCIUM

The calcium salt of zofenopril, a sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, zofenopril… 
National Institutes of Health

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zofenopril

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Highly Cited
2014
Highly Cited
2014
Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition.
AIMS Therapeutic use of sulfhydrylated inhibitor S-zofenopril has raised different hypotheses regarding the role played by its… 
Highly Cited
2006
Highly Cited
2006
Gateways to clinical trials.
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2004
2004
11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat.
2002
2002
Pharmacokinetic and pharmacodynamic comparative study of zofenopril and enalapril in healthy volunteers.
Zofenopril calcium (CAS 81938-43-4) is a new angiotensin converting enzyme (ACE) inhibitor, which in addition to the typical… 
2000
2000
Assay of zofenopril and its active metabolite zofenoprilat by liquid chromatography coupled with tandem mass spectrometry.
Review
1999
Review
1999
Preclinical Profile of Zofenopril: An Angiotensin Converting Enzyme Inhibitor with Peculiar Cardioprotective Properties
The discovery of captopril, the prototype of orally active angiotensin-converting enzyme inhibitors (ACEIs), represented a major… 
Review
1994
Review
1994
Survival of myocardial infarction long-term evaluation (SMILE) study: rationale, design, organization, and outcome definitions.
Highly Cited
1993
Highly Cited
1993
Evidence of a Partial Escape of Renin‐Angiotensin‐Aldosterone Blockade in Patients with Acute Myocardial Infarction Treated with Ace Inhibitors
Angiotensin‐Converting enzyme (ACE) inhibitors have been designed to block the renin‐angiotensin system and can represent an… 
1990
1990
Disposition of zofenopril calcium in healthy subjects.
Zofenopril calcium (1) is a prodrug that is hydrolyzed in vivo to the active angiotensin-converting enzyme (ACE) inhibitor SQ 26… 
1989
1989
Preclinical Pharmacology of Zofenopril, an Inhibitor of Angiotensin I Converting Enzyme
Summary: Zofenopril calcium (one-half calcium salt) is a prodrug ester analog of captopril whose biological effects are… 
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