FAQ

ZNF217 wt Allele

Known as: ZABC1, ZNF217, Zinc Finger Protein 217 wt Allele 
Human ZNF217 wild-type allele is located in the vicinity of 20q13.2 and is approximately 16 kb in length. This allele, which encodes zinc finger… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
01220052017

Related topics

Related topics

6 relations
20q13.2Ligand BindingTranscriptional RegulationZNF217 gene
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Related mentions per year

Related mentions per year

1961-2018
1960198020002020
ZNF217 wt Allele
Transcriptional Regulation
dna binding
Ligand Binding
20q13.2
ZNF217 gene

Papers overview

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2016
2016
Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts
Abnormally high activation of transforming growth factor-β (TGF-β) signaling has been demonstrated to be involved in the… (More)
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2014
2014
MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer.
Resistance to trastuzumab and concomitantly distal metastasis are leading causes of mortality in HER2-positive breast cancers… (More)
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2014
2014
A functional interplay between ZNF217 and estrogen receptor alpha exists in luminal breast cancers.
We aimed at highlighting the role of ZNF217, a Krüppel-like finger protein, in Estrogen Receptor-α (ERα)-positive (ER+) and… (More)
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2014
2014
ZNF217 is associated with poor prognosis and enhances proliferation and metastasis in ovarian cancer.
ZNF217 is an alternatively spliced Kruppel-like transcription factor that has recently been implicated to play a role in human… (More)
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2010
2010
ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells
ZNF217 is a candidate oncogene located at 20q13, a chromosomal region frequently amplified in breast cancers. The precise… (More)
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2010
2010
ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells
Understanding the mechanisms underlying ErbB3 overexpression in breast cancer will facilitate the rational design of therapies to… (More)
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2008
2008
Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays.
We applied whole-genome single-nucleotide polymorphism arrays to define a comprehensive genetic profile of 23 esophageal… (More)
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2008
2008
The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas.
Ovarian epithelial carcinomas (OECs) frequently exhibit amplifications at the 20q13 locus which is the site of several oncogenes… (More)
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2007
2007
Molecular genetic aberrations of ovarian and uterine carcinosarcomas—a CGH and FISH study
The origin of carcinosarcomas of the ovary and uterus has long been discussed. In this study, we used a molecular–genetic… (More)
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2005
2005
ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction.
Chromosome 20q13.2 is amplified in 20-30% of early-stage breast tumors and is associated with poor prognosis. Detailed mapping of… (More)
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