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ZNF217 wt Allele

Known as: ZABC1, ZNF217, Zinc Finger Protein 217 wt Allele 
Human ZNF217 wild-type allele is located in the vicinity of 20q13.2 and is approximately 16 kb in length. This allele, which encodes zinc finger… 
National Institutes of Health

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6 relations
20q13.2Ligand BindingTranscriptional RegulationZNF217 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Weighted Gene Correlation Network Analysis (WGCNA) Reveals Novel Transcription Factors Associated With Bisphenol A Dose-Response
Despite Bisphenol-A (BPA) being subject to extensive study, a thorough understanding of molecular mechanism remains elusive. Here… 
Review
2017
Review
2017
Beyond Transcription: Roles of Transcription Factors in Pre-mRNA Splicing.
Whereas individual steps of protein-coding gene expression in eukaryotes can be studied in isolation in vitro, it has become… 
Highly Cited
2016
Highly Cited
2016
Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts
Abnormally high activation of transforming growth factor-β (TGF-β) signaling has been demonstrated to be involved in the… 
Highly Cited
2014
Highly Cited
2014
MiR‐200c suppresses TGF‐β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer
Resistance to trastuzumab and concomitantly distal metastasis are leading causes of mortality in HER2‐positive breast cancers… 
2010
2010
ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells
Understanding the mechanisms underlying ErbB3 overexpression in breast cancer will facilitate the rational design of therapies to… 
Highly Cited
2008
Highly Cited
2008
Genome Analysis Identifies the p15ink4b Tumor Suppressor as a Direct Target of the ZNF217/CoREST Complex
ABSTRACT The ZNF217 oncoprotein is a constituent of a core transcriptional complex that includes CoREST, histone deacetylase 1/2… 
Highly Cited
2005
Highly Cited
2005
ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction.
Chromosome 20q13.2 is amplified in 20-30% of early-stage breast tumors and is associated with poor prognosis. Detailed mapping of… 
Review
2005
Review
2005
Chromosomal instability in flat adenomas and carcinomas of the colon
Flat adenomas are flat or slightly elevated dysplastic lesions of the colorectal mucosa, mostly with a tubular architecture… 
Highly Cited
2003
Highly Cited
2003
Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas.
Primary cutaneous lymphomas (PCLs) represent a heterogeneous group of extranodal T- and B-cell malignancies. The underlying… 
Highly Cited
2000
Highly Cited
2000
Differences in 20q13.2 copy number between colorectal cancers with and without liver metastasis.
Frequent gains of 20q have been identified recently in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon… 
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