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ZNF217 protein, human

Known as: zinc finger protein 217, human, ZNF217 Protein, Zinc Finger Protein 217 
Zinc finger protein 217 (1048 aa, ~115 kDa) is encoded by the human ZNF217 gene. This protein plays a role in the negative regulation of… Expand
National Institutes of Health

Related topics

Related topics

13 relations
CYS2-HIS2 Zinc FingersDNA-Binding ProteinsGenes, RegulatorProline-Rich Domain
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Broader (1)

Trans-Activators

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone
Bone metastasis affects >70% of patients with advanced breast cancer. However, the molecular mechanisms underlying this process… Expand
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2014
2014
A functional interplay between ZNF217 and estrogen receptor alpha exists in luminal breast cancers.
We aimed at highlighting the role of ZNF217, a Krüppel-like finger protein, in Estrogen Receptor-α (ERα)-positive (ER+) and… Expand
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2012
2012
The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression.
UNLABELLED The transcription factor ZNF217 is a candidate oncogene in the amplicon on chromosome 20q13 that occurs in 20% to 30… Expand
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2011
2011
Rôle de ZNF217, un nouvel oncogène dans le cancer du sein : rôle dans l’échappement tumoral et valeur pronostique
ZNF217, un nouveau membre de la famille kruppel-like, est un facteur de transcription qui interagit avec des co-represseurs et… Expand
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2010
2010
ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells
BackgroundZNF217 is a candidate oncogene located at 20q13, a chromosomal region frequently amplified in breast cancers. The… Expand
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2008
2008
Identification of a Second CtBP Binding Site in Adenovirus Type 5 E1A Conserved Region 3
ABSTRACT C-terminal binding protein (CtBP) binds to adenovirus early region 1A (AdE1A) through a highly conserved PXDLS motif… Expand
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2008
2008
The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas.
Ovarian epithelial carcinomas (OECs) frequently exhibit amplifications at the 20q13 locus which is the site of several oncogenes… Expand
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Highly Cited
2007
Highly Cited
2007
Identification of Genes Directly Regulated by the Oncogene ZNF217 Using Chromatin Immunoprecipitation (ChIP)-Chip Assays*
It has been proposed that ZNF217, which is amplified at 20q13 in various tumors, plays a key role during neoplastic… Expand
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Highly Cited
2006
Highly Cited
2006
Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins
ABSTRACT Numerous transcription factors recruit C-terminal binding protein (CtBP) corepressors. We show that the large zinc… Expand
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2005
2005
ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction.
Chromosome 20q13.2 is amplified in 20-30% of early-stage breast tumors and is associated with poor prognosis. Detailed mapping of… Expand
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