ZM 447439

Known as: ZM-447439, ZM447439 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
0520032017

Papers overview

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2008
2008
Mitotic Aurora kinases are essential for accurate chromosome segregation during cell division. Forced overexpression of Aurora… (More)
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2008
2008
Aurora kinases have emerged as potential targets in cancer therapy, and several drugs are currently undergoing preclinical and… (More)
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Highly Cited
2007
Highly Cited
2007
Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. We have recently… (More)
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2007
2007
VX-680, also known as MK-0457, is a member of a diverse group of small molecules that inhibit the Aurora kinases, and has shown… (More)
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Highly Cited
2007
Highly Cited
2007
The Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. Aberrant… (More)
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Highly Cited
2006
Highly Cited
2006
Merotelic kinetochore orientation is a misattachment in which a single kinetochore binds microtubules from both spindle poles… (More)
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Highly Cited
2006
Highly Cited
2006
The Aurora kinases, a family of mitotic regulators, have received much attention as potential targets for novel anti-cancer… (More)
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Highly Cited
2005
Highly Cited
2005
The spindle checkpoint maintains genome stability by inhibiting Cdc20-mediated activation of the anaphase promoting complex… (More)
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2005
2005
The Aurora family kinases contribute to accurate progression through several mitotic events. ZM447439 ("ZM"), the first Aurora… (More)
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Highly Cited
2003
Highly Cited
2003
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… (More)
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