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ZM 447439

Known as: ZM-447439, ZM447439 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The mitotic Aurora kinases, including Aurora-A and Aurora- B, are attractive novel targets for anticancer therapy, and inhibitory… Expand
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Highly Cited
2008
Highly Cited
2008
Aurora kinase inhibitors are being considered for treatment of acute myeloid leukemia. Findings of this study suggest that two… Expand
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Highly Cited
2008
Highly Cited
2008
Aurora kinases have emerged as potential targets in cancer therapy, and several drugs are currently undergoing preclinical and… Expand
Highly Cited
2007
Highly Cited
2007
Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. We have recently… Expand
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Highly Cited
2007
Highly Cited
2007
The Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. Aberrant… Expand
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Highly Cited
2006
Highly Cited
2006
Merotelic kinetochore orientation is a misattachment in which a single kinetochore binds microtubules from both spindle poles… Expand
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Highly Cited
2006
Highly Cited
2006
The Aurora kinases, a family of mitotic regulators, have received much attention as potential targets for novel anti-cancer… Expand
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Highly Cited
2006
Highly Cited
2006
Oncoprotein 18/Stathmin (Op18) is a microtubule-destabilizing protein that is inhibited by phosphorylation in response to many… Expand
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Highly Cited
2005
Highly Cited
2005
The Aurora family kinases contribute to accurate progression through several mitotic events. ZM447439 ("ZM"), the first Aurora… Expand
Highly Cited
2003
Highly Cited
2003
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… Expand
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