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ZM 447439

Known as: ZM-447439, ZM447439 
 
National Institutes of Health

Papers overview

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2011
2011
Tumor cells are commonly aneuploid, a condition contributing to cancer progression and drug resistance. Understanding how… Expand
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2010
2010
Previous studies have established that when maturing mouse oocytes are continuously incubated with the Aurora inhibitor ZM447439… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Aurora kinases play an essential role in the orchestration of chromosome separation and cytokinesis during mitosis… Expand
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Highly Cited
2007
Highly Cited
2007
Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. We have recently… Expand
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Highly Cited
2007
Highly Cited
2007
The Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. Aberrant… Expand
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Highly Cited
2007
Highly Cited
2007
VX-680, also known as MK-0457, is a member of a diverse group of small molecules that inhibit the Aurora kinases, and has shown… Expand
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Highly Cited
2006
Highly Cited
2006
Merotelic kinetochore orientation is a misattachment in which a single kinetochore binds microtubules from both spindle poles… Expand
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Highly Cited
2006
Highly Cited
2006
The Aurora kinases, a family of mitotic regulators, have received much attention as potential targets for novel anti-cancer… Expand
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Highly Cited
2006
Highly Cited
2006
Oncoprotein 18/Stathmin (Op18) is a microtubule-destabilizing protein that is inhibited by phosphorylation in response to many… Expand
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Highly Cited
2003
Highly Cited
2003
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… Expand
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