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ZK 807834

Known as: ZK-807834 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The ex vivo testing emerges as an essential and critical step for the selection of the most promising prospective anticoagulant… Expand
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2007
2007
It was the objective of this study to evaluate the anti-thrombotic potency of direct factor-Xa inhibition with ZK-807834 in… Expand
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2002
2002
ZK-807834 (also known as CI-1031) is a small molecule that potently and selectively inhibits Factor Xa. Studies in animals have… Expand
2002
2002
CI-1031 (ZK-807834) is a novel, synthetic factor Xa (FXa) inhibitor with a Ki of 0.11 nM against human FXa. In human plasma in… Expand
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2001
2001
During thrombosis, vascular wall cells are exposed to clotting factors, including the procoagulant proteases thrombin and factor… Expand
2001
2001
Factor Xa is a serine protease positioned at the convergence point of the intrinsic and extrinsic coagulation pathways and is… Expand
2001
2001
Inhibition of factor Xa (FXa) attenuates thrombus progression. This study was designed to determine whether a novel, synthetic… Expand
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Highly Cited
2000
Highly Cited
2000
Factor Xa plays a critical role in the formation of blood clots. This serine protease catalyzes the conversion of prothrombin to… Expand
2000
2000
Inhibition of factor Xa (FXa) may interrupt thrombus progression. This study compared the antithrombotic activity of a novel FXa… Expand