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The mechanisms involved in the epithelial to mesenchymal transition (EMT) are integrated in concert with master developmental and… Expand Glioma has been considered resistant to chemotherapy and radiation. Recently, concomitant and adjuvant chemoradiotherapy with… Expand Angiogenesis plays a central role in the process of tumor growth and metastatic dissemination. The vascular endothelial growth… Expand BACKGROUND
ZD6474 selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor and epidermal… Expand To realize the full potential of targeted protein kinase inhibitors for the treatment of cancer, it is important to address the… Expand Purpose: The epidermal growth factor receptor (EGFR) autocrine signaling pathway is involved in cancer development and… Expand PURPOSE
Vascular endothelial growth factor (VEGF) is a major mitogen for endothelial cells and enhances vascular permeability… Expand ZD6474 [N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine]is a potent, p.o. active, low… Expand RET/papillary thyroid carcinoma (PTC) oncogenes, generated by recombination of the tyrosine kinase-encoding domain of RET with… Expand The activity of thymulin (a thymic hormone) is dependent on the presence of zinc in the molecule. We assayed serum thymulin… Expand