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ZD 6021
Known as:
(3-cyano-N-(2-(3,4-dichlorophenyl)-4-(4-(2-(methylsulfinyl)phenyl)piperidino)butyl)-N-methyl)naphthamide
, ZD-6021
, ZD6021
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Piperidines
Sulfoxides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3.
Agnes Leffler
,
I. Ahlstedt
,
+6 authors
B. von Mentzer
Biochemical pharmacology
2009
Corpus ID: 31319162
2008
2008
Occurrence and pharmacological characterization of four human tachykinin NK2 receptor variants.
I. Ahlstedt
,
S. Engberg
,
+8 authors
E. Lindström
Biochemical pharmacology
2008
Corpus ID: 11257524
Highly Cited
2007
Highly Cited
2007
Neurokinin 1 Receptor Antagonists: Correlation between in Vitro Receptor Interaction and in Vivo Efficacy
E. Lindström
,
B. von Mentzer
,
+7 authors
G. Vauquelin
Journal of Pharmacology and Experimental…
2007
Corpus ID: 14148413
We compared the neurokinin 1 receptor (NK1R) antagonists aprepitant, CP-99994 [(2S,3S)-3-(2-methoxybenzylamino)-2…
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2007
2007
Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors.
S. Engberg
,
I. Ahlstedt
,
+7 authors
B. von Mentzer
Biochemical pharmacology
2007
Corpus ID: 5930207
2004
2004
Glutamate and tachykinin receptors in central sensitization of withdrawal reflexes in the decerebrated rabbit
J. Harris
,
C. Joules
,
C. Stanley
,
P. Thomas
,
R. Clarke
Experimental physiology
2004
Corpus ID: 39928044
This study assessed the involvement of NMDA and group I metabotropic glutamate receptors, and tachykinin NK1 and NK3 receptors…
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2002
2002
Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity.
J. Albert
,
D. Aharony
,
+18 authors
K. Russell
Journal of medicinal chemistry
2002
Corpus ID: 19879722
Through optimization of compounds based on the dual NK(1)/NK(2) antagonist ZD6021, it was found that alteration of two key…
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2001
2001
Discovery of novel, orally active dual NK1/NK2 antagonists.
P. Bernstein
,
D. Aharony
,
+17 authors
K. Russell
Bioorganic & medicinal chemistry letters
2001
Corpus ID: 25050654
2001
2001
Pharmacological characterization of ZD6021: a novel, orally active antagonist of the tachykinin receptors.
W. Rumsey
,
D. Aharony
,
+14 authors
K. Russell
The Journal of pharmacology and experimental…
2001
Corpus ID: 39588526
The tachykinins, substance P, neurokinin A, and neurokinin B, have been implicated in many diseases. The present study evaluated…
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