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, zinc finger CCCH-type containing 18
National Institutes of Health
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Affinity Proteomic Analysis of the Human Exosome and Its Cofactor Complexes.
Methods in molecular biology
Corpus ID: 208298975
In humans, the RNA exosome consists of an enzymatically inactive nine-subunit core, with ribonucleolytic activity contributed by…
ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer
Corpus ID: 204054880
Reduced BRCA1 expression causes homologous recombination (HR) repair defects in high-grade serous ovarian cancers (HGSOCs). Here…
Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate
Nour el Houda Benbahouche
Corpus ID: 4575700
Summary The nuclear cap-binding complex (CBC) stimulates processing reactions of capped RNAs, including their splicing, 3′-end…
A Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18
Nucleic acids research
Corpus ID: 18720202
Viral RNA elements that facilitate mRNA export are useful tools for identifying cellular RNA export factors. Here we show that…
Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia.
Corpus ID: 282879
Severe congenital neutropenia (SCN) is a BM failure syndrome with a high risk of progression to acute myeloid leukemia (AML). The…
The Trypanosoma brucei zinc finger protein ZC3H18 is involved in differentiation.
Molecular and biochemical parasitology
Corpus ID: 33581135
In mammalian cells, the degradation of mRNAs that have AU-rich elements in their 3'-untranslated regions is accelerated by the…
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