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Yeast Model System

Known as: Yeast Model 
Pathways and other molecular and cellular processes which can be manipulated in yeast, the results of which can be extrapolated to human systems.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Background: The intrinsically disordered protein α-synuclein, a hallmark of Parkinson disease, is involved in mitochondrial… Expand
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Highly Cited
2014
Highly Cited
2014
Exonucleolytic proofreading and DNA mismatch repair (MMR) act in series to maintain high-fidelity DNA replication and to avoid… Expand
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2013
2013
The assembly of the viral replicase complex (VRC) on subcellular membranes is a key step in the replication process of plus… Expand
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2012
2012
Programmed cell death (PCD) is an essential cellular mechanism that is evolutionary conserved, mediated through various pathways… Expand
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Review
2012
Review
2012
Throughout the kingdoms of life, transfer RNA (tRNA) undergoes over 100 enzyme-catalyzed, methyl-based modifications. Although a… Expand
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Review
2008
Review
2008
Alteration of the epigenome is associated with a wide range of human diseases. Therefore, deciphering the pathways that regulate… Expand
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Review
2007
Review
2007
Yeast self-perpetuating amyloids (prions) provide a convenient model for studying the cellular control of highly ordered… Expand
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Highly Cited
2005
Highly Cited
2005
In yeast, aggregation and toxicity of the expanded polyglutamine fragment of human huntingtin strictly depend on the presence of… Expand
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2005
2005
A yeast model was generated to study the mechanisms and phenotypical repercussions of expression of alpha-synuclein as well as… Expand
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Highly Cited
2004
Highly Cited
2004
The key protein in Alzheimer's disease, the amyloid precursor protein (APP), is a ubiquitously expressed copper-binding… Expand
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