Xanthine Oxidase Inhibitors

Known as: Xanthine Oxidase Inhibitor 
Any substance that inhibits xanthine oxidase, an enzyme that catalyzes the oxidation of hypoxanthine to xanthine and xanthine to uric acid, along… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Elevated levels of C-reactive protein (CRP), a proinflammatory marker, are associated with reduced systemic endothelium… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Angiotensin II-induced hypertension is associated with NAD(P)H oxidase-dependent superoxide production in the vessel… (More)
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Highly Cited
2002
Highly Cited
2002
Hyperuricemia is associated with renal disease, but it is usually considered a marker of renal dysfunction rather than a risk… (More)
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2002
2002
Apoptotic degeneration of germ cells in cryptorchid testis is associated with an increased level of reactive oxygen species, and… (More)
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Highly Cited
2001
Highly Cited
2001
We previously reported increased aortic reactive oxygen species (ROS) production in mineralocorticoid (deoxycorticosterone… (More)
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Highly Cited
2001
Highly Cited
2001
An elevation in circulating serum uric acid is strongly associated with the development of hypertension and renal disease, but… (More)
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Highly Cited
1998
Highly Cited
1998
The structure-activity relationship of flavonoids as inhibitors of xanthine oxidase and as scavengers of the superoxide radical… (More)
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Highly Cited
1986
Highly Cited
1986
Previous reports indicate that allopurinol, a xanthine oxidase inhibitor, largely prevents the injury produced by reperfusion of… (More)
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Highly Cited
1983
Highly Cited
1983
The results of previous studies indicate that oxygen-derived free radicals are responsible for the increased vascular… (More)
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