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XV 459

Known as: XV-459, XV459 
 
National Institutes of Health

Papers overview

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2007
2007
Heparin-induced thrombocytopenia (HIT) is a serious, immune-related complication of heparin therapy. One of the most severe… Expand
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2007
2007
  • Shaker A. Mousa
  • Blood coagulation & fibrinolysis : an…
  • 2007
  • Corpus ID: 23614288
Suppressing platelet activation improves efficacy of thrombolytic therapy for stroke and acute myocardial infarction. Combination… Expand
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2002
2002
Roxifiban is an oral prodrug of XV459, a potent and specific inhibitor of the glycoprotein (GP) IIb/IIIa receptor previously… Expand
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2002
2002
Roxifiban is an esterprodrug that is hydrolyzed, after oral administration, to the active glycoprotein (GP) IIb/IIIa antagonist… Expand
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2001
2001
The effect of various platelet glycoprotein IIb/IIIa (GPIIb/IIIa) antagonists on the dynamics of platelet-fibrin clot formation… Expand
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2000
2000
In the present study, the in vitro efficacy of different platelet glycoprotein IIb/IIIa (GPIIb/IIIa) antagonists on platelet… Expand
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1999
1999
Currently used antiplatelet drugs, including aspirin, ticlopidine, and others, are effective against certain but not all of the… Expand
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1998
1998
The effects of the platelet alphaIIb beta3 integrin (GPIIb/IIIa) antagonists XV459 (non-peptide), c7E3 (Fab monoclonal antibody… Expand
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1998
1998
Recent advances in the development of i.v. platelet glycoprotein alphaIIb/beta3 integrin (GPIIb/IIIa) antagonists led to the… Expand
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1996
1996
OBJECTIVE To define the antiplatelet efficacy and specificity of the glycoprotein IIb/IIIa complex (GPIIb/IIIa) antagonist… Expand
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