XRCC4 protein, human

Known as: X-ray repair complementing defective repair in Chinese hamster cells 4, human, DNA Repair Protein XRCC4, X-Ray Repair, Complementing Defective, Repair In Chinese Hamster 
DNA repair protein XRCC4 (336 aa, ~38 kDa) is encoded by the human XRCC4 gene. This protein plays a role in DNA non-homologous end joining, which is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
DNA nonhomologous end-joining (NHEJ) is a predominant pathway of DNA double-strand break repair in mammalian cells, and defects… (More)
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Highly Cited
2006
Highly Cited
2006
DNA double-strand break (DSB) repair by nonhomologous end joining (NHEJ) requires the assembly of several proteins on DNA ends… (More)
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Highly Cited
2005
Highly Cited
2005
Repair of DNA double strand breaks (DSBs) by the non-homologous end joining (NHEJ) pathway in mammals requires at least the DNA… (More)
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Highly Cited
2004
Highly Cited
2004
Ataxia-oculomotor apraxia 1 (AOA1) is an autosomal recessive neurodegenerative disease that is reminiscent of ataxia… (More)
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Highly Cited
2000
Highly Cited
2000
XRCC4 is a non-homologous end-joining protein employed in DNA double strand break repair and in V(D)J recombination. In mice… (More)
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Highly Cited
1999
Highly Cited
1999
XR-1 is a CHO mutant cell line defective in double strand break repair and V(D)J recombination. These defects are due to a… (More)
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Highly Cited
1998
Highly Cited
1998
The gene product of XRCC4 has been implicated in both V(D)J recombination and the more general process of double strand break… (More)
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Highly Cited
1998
Highly Cited
1998
The Ku86 and XRCC4 proteins perform critical but poorly understood functions in the repair of DNA double-strand breaks. Both Ku… (More)
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Highly Cited
1997
Highly Cited
1997
Mutation of the XRCC4 gene in mammalian cells prevents the formation of the signal and coding joints in the V(D)J recombination… (More)
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Highly Cited
1995
Highly Cited
1995
The XR-1 Chinese hamster ovary cell line is impaired in DNA double-strand break repair (DSBR) and in ability to support V(D)J… (More)
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