XRCC3 protein, human

Known as: DNA Repair Protein XRCC3, XRCC3, X-Ray Repair Cross-Complementing Protein 3 
DNA repair protein XRCC3 (346 aa, ~38 kDa) is encoded by the human XRCC3 gene. This protein is involved in homologous recombination repair of double… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Polymorphisms in DNA repair genes have been associated to repair DNA lesions, and might contribute to the individual… (More)
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Highly Cited
2003
Highly Cited
2003
The mechanisms by which the progression of eukaryotic replication forks is controlled after DNA damage are unclear. We have found… (More)
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Highly Cited
2003
Highly Cited
2003
Mammalian cells are constantly exposed to a wide variety of genotoxic agents from both endogenous and exogenous sources. Genetic… (More)
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Highly Cited
2002
Highly Cited
2002
XRCC3 is a RAD51 paralog that functions in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR). XRCC3… (More)
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Highly Cited
2001
Highly Cited
2001
DNA repair genes have an important role in protecting individuals from cancer-causing agents. Polymorphisms in several DNA repair… (More)
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Highly Cited
2000
Highly Cited
2000
XRCC3 was originally identified as a human gene able to complement the DNA damage sensitivity, chromosomal instability and… (More)
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Highly Cited
2000
Highly Cited
2000
In yeast, the Rad51-related proteins include Rad55 and Rad57, which form a heterodimer that interacts with Rad51. Five human… (More)
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Highly Cited
1999
Highly Cited
1999
Homology-directed repair of DNA damage has recently emerged as a major mechanism for the maintenance of genomic integrity in… (More)
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Highly Cited
1998
Highly Cited
1998
The phenotypically similar hamster mutants irs1 and irs1SF exhibit high spontaneous chromosome instability and broad-spectrum… (More)
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Highly Cited
1995
Highly Cited
1995
The mutagen-sensitive CHO line irs1SF was previously isolated on the basis of hypersensitivity to ionizing radiation and was… (More)
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