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XRCC3 protein, human

Known as: DNA Repair Protein XRCC3, XRCC3, X-Ray Repair Cross-Complementing Protein 3 
DNA repair protein XRCC3 (346 aa, ~38 kDa) is encoded by the human XRCC3 gene. This protein is involved in homologous recombination repair of double… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Summary Faithful DNA replication is essential to all life. Hydroxyurea (HU) depletes the cells of dNTPs, which initially results… Expand
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Highly Cited
2004
Highly Cited
2004
We investigated the association of urinary bladder cancer with genetic polymorphisms in the xeroderma pigmentosum complementation… Expand
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Highly Cited
2003
Highly Cited
2003
A major barrier to understanding the role of polymorphic DNA repair genes for environmental cancer is that the functions of… Expand
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Highly Cited
2002
Highly Cited
2002
We performed genetic association studies in a population-based breast cancer case-control study analysing polymorphisms in genes… Expand
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Highly Cited
2001
Highly Cited
2001
DNA repair genes have an important role in protecting individuals from cancer-causing agents. Polymorphisms in several DNA repair… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT The mechanisms by which DNA interstrand cross-links (ICLs) are repaired in mammalian cells are unclear. Studies in… Expand
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Highly Cited
2000
Highly Cited
2000
In yeast, the Rad51-related proteins include Rad55 and Rad57, which form a heterodimer that interacts with Rad51. Five human… Expand
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Highly Cited
1999
Highly Cited
1999
Homology-directed repair of DNA damage has recently emerged as a major mechanism for the maintenance of genomic integrity in… Expand
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Highly Cited
1998
Highly Cited
1998
The phenotypically similar hamster mutants irs1 and irs1SF exhibit high spontaneous chromosome instability and broad-spectrum… Expand
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Highly Cited
1995
Highly Cited
1995
The mutagen-sensitive CHO line irs1SF was previously isolated on the basis of hypersensitivity to ionizing radiation and was… Expand
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