XPA wt Allele

Known as: XP, Group A Gene, XPA Correcting Gene, XPA 
Human XPA wild-type allele is located in the vicinity of 9q22.3 and is approximately 22 kb in length. This allele, which encodes DNA-repair protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
DNA repair function is believed to play an important role in cancer development and to be affected by genetic polymorphisms… (More)
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Highly Cited
2010
Highly Cited
2010
Risk factors for gastric cancer (GC) include inter-individual variability in the inflammatory response to Helicobacter pylori… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Exposure to environmental carcinogens leads to oral squamous cell carcinoma (OSCC); however, the impact of genetic… (More)
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Highly Cited
2005
Highly Cited
2005
Nucleotide excision repair (NER) is the major DNA repair process that removes diverse DNA lesions including UV-induced… (More)
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Highly Cited
2004
Highly Cited
2004
Over 80% of patients with advanced metastatic testis tumors can be cured using cisplatin-based combination chemotherapy. This is… (More)
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Highly Cited
2004
Highly Cited
2004
Several polymorphisms in DNA repair genes have been reported to be associated with lung cancer risk including XPA (-4G/A), XPD… (More)
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Highly Cited
2003
Highly Cited
2003
Oxaliplatin (L-OHP) is a new platinum analogue that has shown antitumour activity against colon cancer both in vitro and in vivo… (More)
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Highly Cited
2001
Highly Cited
2001
Purpose: We have previously reported that elevation of glutathione mediated by γ-glutamyl transpeptidase is one mechanism of… (More)
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Highly Cited
1995
Highly Cited
1995
XERODERM A pigmentosum patients with a defect in the nucleotide-excision repair gene XPA are characterized by, for example, a > 1… (More)
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Highly Cited
1994
Highly Cited
1994
Nucleotide excision repair is a DNA repair pathway that is highly conserved in nature, with analogous repair systems described in… (More)
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