XPA gene

Known as: Xeroderma Pigmentosum, Complementation Group A Gene, XP1, XPA COMPLEMENTING GENE 
This gene facilitates DNA binding in repair processes and is associated with the disease xeroderma pigmentosum complementation group A.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Many studies have detailed the repressive effects of DNA methylation on gene expression. However, the mechanisms that promote… (More)
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Highly Cited
2006
Highly Cited
2006
Lung cancer is a leading cause of cancer mortality with an inter-individual difference in susceptibility to the disease. The… (More)
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Highly Cited
2004
Highly Cited
2004
Over 80% of patients with advanced metastatic testis tumors can be cured using cisplatin-based combination chemotherapy. This is… (More)
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Highly Cited
2003
Highly Cited
2003
XPA, a DNA binding protein in the nucleotide excision repair (NER) pathway, modulates damage recognition. Recently, a common… (More)
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Highly Cited
2001
Highly Cited
2001
The multiprotein factor composed of XPA and replication protein A (RPA) is an essential subunit of the mammalian nucleotide… (More)
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Highly Cited
2001
Highly Cited
2001
The DNA repair protein XPA recognizes a wide variety of bulky lesions and interacts with several other proteins during nucleotide… (More)
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Highly Cited
2000
Highly Cited
2000
Replication protein A (RPA), the nuclear ssDNA-binding protein in eukaryotes, is essential to DNA replication, recombination, and… (More)
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Highly Cited
1998
Highly Cited
1998
The XPC-HR23B complex is specifically involved in global genome but not transcription-coupled nucleotide excision repair (NER… (More)
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Highly Cited
1995
Highly Cited
1995
XERODERM A pigmentosum patients with a defect in the nucleotide-excision repair gene XPA are characterized by, for example, a > 1… (More)
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Highly Cited
1994
Highly Cited
1994
Processing of DNA damage by the nucleotide-excision repair pathway in eukaryotic cells is most likely accomplished by… (More)
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