Wiskott-Aldrich Syndrome

Known as: aldrich syndrome wiskott, Syndrome, Eczema-Thrombocytopenia-Immunodeficiency, eczema thromocytopenia immunodeficiency syndrome 
An inherited immune disorder that occurs in young boys. It causes eczema (a type of skin inflammation), a decrease in the number of platelets (blood… (More)
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
IMPORTANCE Wiskott-Aldrich syndrome is a rare primary immunodeficiency associated with severe microthrombocytopenia. Partially… (More)
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Highly Cited
2014
Highly Cited
2014
Wiskott-Aldrich syndrome (WAS) is characterized by microthrombocytopenia, immunodeficiency, autoimmunity, and susceptibility to… (More)
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Highly Cited
2000
Highly Cited
2000
The Rho-family GTPase, Cdc42, can regulate the actin cytoskeleton through activation of Wiskott–Aldrich syndrome protein (WASP… (More)
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Highly Cited
2000
Highly Cited
2000
Interactions between the Wiskott-Aldrich (WAS) protein (WASp), small GTPases, and the cytoskeletal organizing complex Arp2/3… (More)
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Highly Cited
1999
Highly Cited
1999
The Rho-family GTP-hydrolysing proteins (GTPases), Cdc42, Rac and Rho, act as molecular switches in signalling pathways that… (More)
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Review
1998
Review
1998
In 1937, Wiskott described three brothers with congenital thrombocytopenia, bloody diarrhea, eczema, and recurrent ear infections… (More)
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Highly Cited
1997
Highly Cited
1997
Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT), caused by mutations of the WAS protein (WASP) gene, represent… (More)
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Highly Cited
1996
Highly Cited
1996
The Rho family of GTPases control diverse biological processes, including cell morphology and mitogenesis. We have identified… (More)
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1988
1988
The Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disease characterized by immunodeficiency and severe thrombocytopenia… (More)
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Review
1978
Review
1978
Individuals with Wiskott-Aldrich syndrome have microthrombocytopenia, which is a decrease in the number and size of blood cell… (More)
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