Widespread Disease

Known as: Extensive Disease, Generalized Disease 
A pathologic process that has spread from its original site of growth to multiple distant anatomic sites.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
05010015019362016

Papers overview

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Highly Cited
2009
Highly Cited
2009
The number and volume of cells in the blood affect a wide range of disorders including cancer and cardiovascular, metabolic… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND AND AIMS Mucosal healing (MH) in inflammatory bowel disease may be an important sign of efficacy of treatment and a… (More)
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Highly Cited
2004
Highly Cited
2004
CONTEXT Among men with early prostate cancer, the natural history without initial therapy determines the potential for survival… (More)
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Highly Cited
2004
Highly Cited
2004
Most patients with plasma cell neoplasia have generalized disease at diagnosis, i.e. multiple myeloma (MM). However, a minority… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Despite aggressive local therapy, patients with locally advanced bladder cancer are at significant risk for metastases… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND In spite of 16 randomized trials conducted during the past 15 years, the effect of thoracic radiotherapy on the… (More)
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Highly Cited
1991
Highly Cited
1991
In a variety of plant species, the development of necrotic lesions in response to pathogen infection leads to induction of… (More)
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Highly Cited
1990
Highly Cited
1990
BACKGROUND The risk of colorectal cancer is increased among patients with ulcerative colitis. The magnitude of this increase in… (More)
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Highly Cited
1981
Highly Cited
1981
Fifty-two of 175 (30%) survivors of allogeneic marrow transplantation developed chronic graft-versus-hose diseases (GVHD). Five… (More)
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Highly Cited
1980
Highly Cited
1980
This study of chronic graft-versus-host disease (GVHD) describes the clinical, pathologic and laboratory features, and the causes… (More)
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