Whole Genome Amplification

Known as: WGA, Whole Genome PCR 
Any technique designed to amplify a limited genomic DNA sample so as to generate a new sample that is indistinguishable from the original but with a… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Single-cell sequencing is emerging as an important tool for studies of genomic heterogeneity. Whole genome amplification (WGA) is… (More)
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Highly Cited
2011
Highly Cited
2011
Single cell genomics is a powerful and increasingly popular tool for studying the genetic make-up of uncultured microbes. A key… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Single-cell genome sequencing has the potential to allow the in-depth exploration of the vast genetic diversity found… (More)
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Highly Cited
2006
Highly Cited
2006
Whole genome amplification is an increasingly common technique through which minute amounts of DNA can be multiplied to generate… (More)
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Highly Cited
2004
Highly Cited
2004
Major efforts are underway to systematically define the somatic and germline genetic variations causally associated with disease… (More)
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Highly Cited
2002
Highly Cited
2002
Fundamental to most genetic analysis is availability of genomic DNA of adequate quality and quantity. Because DNA yield from… (More)
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Highly Cited
2000
Highly Cited
2000
Analysis of small numbers of chromosomes using interphase fluorescent in-situ hybridization (FISH) probes has revealed that 50… (More)
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Highly Cited
1999
Highly Cited
1999
Molecular genetic analysis of isolated single cells and other minute DNA samples is limited because there is insufficient DNA to… (More)
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Highly Cited
1999
Highly Cited
1999
Combining whole genome amplification (WGA) methods with novel laser-based microdissection techniques has made it possible to… (More)
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Highly Cited
1992
Highly Cited
1992
We have developed an in vitro method for amplifying a large fraction of the DNA sequences present in a single haploid cell by… (More)
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