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Warburg Effect
This effect refers to the high cellular levels of lactic acid in tumor cells, and is named after Otto Warburg who worked on photosynthesis. Tumor…
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National Institutes of Health
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Glycolysis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
The Warburg effect: 80 years on
M. Potter
,
Emma Newport
,
K. Morten
Biochemical Society transactions
2016
Corpus ID: 14587694
Influential research by Warburg and Cori in the 1920s ignited interest in how cancer cells' energy generation is different from…
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Review
2016
Review
2016
Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism
A. Otto
Cancer & metabolism
2016
Corpus ID: 23503461
Virtually everyone working in cancer research is familiar with the “Warburg effect”, i.e., anaerobic glycolysis in the presence…
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Review
2016
Review
2016
The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate
P. Lis
,
M. Dyląg
,
+4 authors
S. Ułaszewski
Molecules
2016
Corpus ID: 7424028
This review summarizes the current state of knowledge about the metabolism of cancer cells, especially with respect to the…
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Highly Cited
2016
Highly Cited
2016
A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway
Jing Liu
,
C. Pan
,
+5 authors
Q. Zuo
Journal of Hematology & Oncology
2016
Corpus ID: 1562734
BackgroundTrastuzumab, a humanized antibody targeting HER2, exhibits remarkable therapeutic efficacy against HER2-positive…
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Review
2016
Review
2016
Warburg Effect - a Consequence or the Cause of Carcinogenesis?
S. Devic
Journal of Cancer
2016
Corpus ID: 1881067
Ever since its discovery (1924) the Warburg effect (aerobic glycolysis) remains an unresolved puzzle: why the aggressive cancer…
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Highly Cited
2015
Highly Cited
2015
Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
G. Bianchi
,
Roberto Martella
,
+12 authors
V. Longo
Oncotarget
2015
Corpus ID: 779729
Tumor chemoresistance is associated with high aerobic glycolysis rates and reduced oxidative phosphorylation, a phenomenon called…
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Review
2014
Review
2014
2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy.
Dongsheng Zhang
,
Juan Li
,
Fengzhen Wang
,
Jun Hu
,
Shuwei Wang
,
Yueming Sun
Cancer letters
2014
Corpus ID: 5178113
Highly Cited
2014
Highly Cited
2014
CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism.
Blake C. Ellis
,
L. Graham
,
P. Molloy
Biochimica et biophysica acta
2014
Corpus ID: 21815155
Review
2013
Review
2013
The Warburg effect then and now: From cancer to inflammatory diseases
E. Pålsson-McDermott
,
L. O’neill
BioEssays : news and reviews in molecular…
2013
Corpus ID: 13259764
Inflammatory immune cells, when activated, display much the same metabolic profile as a glycolytic tumor cell. This involves a…
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Review
2011
Review
2011
Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review
P. Porporato
,
S. Dhup
,
R. Dadhich
,
T. Copetti
,
P. Sonveaux
Front. Pharmacol.
2011
Corpus ID: 14920701
Cancer is a metabolic disease and the solution of two metabolic equations: to produce energy with limited resources and to…
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