Warburg Effect

This effect refers to the high cellular levels of lactic acid in tumor cells, and is named after Otto Warburg who worked on photosynthesis. Tumor… (More)
National Institutes of Health

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Glycolysis

Papers overview

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2017
2017
MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells
The Warburg effect is a well-known feature in cancer-specific metabolism. We previously reported on the role of microRNA (miR… (More)
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Review
2016
Review
2016
The Warburg Effect: How Does it Benefit Cancer Cells?
Cancer cells rewire their metabolism to promote growth, survival, proliferation, and long-term maintenance. The common feature of… (More)
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Review
2016
Review
2016
Warburg Effect - a Consequence or the Cause of Carcinogenesis?
Ever since its discovery (1924) the Warburg effect (aerobic glycolysis) remains an unresolved puzzle: why the aggressive cancer… (More)
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Review
2016
Review
2016
Warburg effect(s)-a biographical sketch of Otto Warburg and his impacts on tumor metabolism.
Virtually everyone working in cancer research is familiar with the "Warburg effect", i.e., anaerobic glycolysis in the presence… (More)
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2016
2016
A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway
BACKGROUND Trastuzumab, a humanized antibody targeting HER2, exhibits remarkable therapeutic efficacy against HER2-positive… (More)
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2015
2015
Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells
BACKGROUND The Warburg effect refers to glycolytic production of adenosine triphosphate under aerobic conditions, and is a… (More)
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2015
2015
Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
Tumor chemoresistance is associated with high aerobic glycolysis rates and reduced oxidative phosphorylation, a phenomenon called… (More)
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Highly Cited
2014
Highly Cited
2014
Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR–STAT3/microRNA143 pathway
Cancer cells preferentially metabolize glucose through aerobic glycolysis, a phenomenon known as the Warburg effect. Emerging… (More)
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Highly Cited
2013
Highly Cited
2013
Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells.
Cancer cell metabolic reprogramming includes a shift in energy production from oxidative phosphorylation to less efficient… (More)
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2012
2012
Glycolysis in preimplantation development is partially controlled by the Warburg Effect.
Glucose metabolism in preimplantation embryos has traditionally been viewed from a somatic cell viewpoint. Here, we show that… (More)
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