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WNT1 protein, human

Known as: WNT1 Gene Product, WNT1 Protein, wingless-type MMTV integration site family, member 1 protein, human 
WNT1 protein is a cysteine-rich secreted glycoprotein homologue of the Drosophila wingless segment-polarity gene product. It is probably a signaling… 
National Institutes of Health

Related topics

Related topics

12 relations
ALK PathwayBeta-Catenin Accumulation PathwayIntercellular Communication ProcessPattern Formation

Broader (1)

Wnt1 Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
H19 knockdown suppresses proliferation and induces apoptosis by regulating miR-148b/WNT/β-catenin in ox-LDL -stimulated vascular smooth muscle cells
Long non-coding RNAs (lncRNAs) have been identified as critical regulators in the development of atherosclerosis (AS). Here, we… 
Highly Cited
2017
Highly Cited
2017
Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis
Mutations in WNT1 cause osteogenesis imperfecta (OI) and early-onset osteoporosis, identifying it as a key Wnt ligand in human… 
2015
2015
Conformational transition of a hairpin structure to G-quadruplex within the WNT1 gene promoter.
The role of G-quadruplexes (G4s) in biological systems has been widely studied. It is found that they have an important function… 
Highly Cited
2015
Highly Cited
2015
MiR-148b suppresses cell proliferation and invasion in hepatocellular carcinoma by targeting WNT1/β-catenin pathway
Accumulating evidences indicate that microRNAs play a vital role in regulating tumor progression. However, the roles of miR-148b… 
Highly Cited
2014
Highly Cited
2014
Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity
Earlier studies reported allelic deletion of the essential autophagy regulator BECN1 in breast cancers implicating BECN1 loss… 
Highly Cited
2013
Highly Cited
2013
WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta.
This report identifies human skeletal diseases associated with mutations in WNT1. In 10 family members with dominantly inherited… 
Highly Cited
2013
Highly Cited
2013
Mutations in WNT1 cause different forms of bone fragility.
Highly Cited
2013
Highly Cited
2013
WNT1 mutations in families affected by moderately severe and progressive recessive osteogenesis imperfecta.
Highly Cited
2004
Highly Cited
2004
Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region
Highly Cited
2000
Highly Cited
2000
SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm.
Dorsoventral polarity of the somitic mesoderm is established by competitive signals originating from adjacent tissues. The… 
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