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WHR-1142A

Known as: WHR- 1142A 
 
National Institutes of Health

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2 relations

Broader (2)

lidamidinelidamidine, hydrochloride

Papers overview

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1983
1983
Absence of mutagenic activity of WHR-1142A, lidamidine hydrochloride, in 4 short-term tests for mutagenic/carcinogenic potential.
WHR-1142A, lidamidine hydrochloride, an antidiarrhoeal agent, was tested for possible mutagenic/carcinogenic activity in the Ames… Expand
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1981
1981
[Double-blind evaluation of the effectiveness of lidamidine hydrochloride (WHR-1142A) vs loperamide vs. placebo in the treatment of acute diarrhea].
 
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1979
1979
[Evaluation of the safety and effectiveness of WHR-1142A in the treatment of non-specific acute diarrhea].
A randomized double-blind placebo controlled trial of the safety and efficacy of lidamidine hydrochloride (WHR-1142A) in thirty… Expand
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1978
1978
In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.
1-(2,6-Dimethylphenyl)-3-methyl-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) was shown to have potent… Expand
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1978
1978
Mechanism of action studies of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.
1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A), lidamidine hydrochloride), a novel antidiarrheal agent… Expand
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1978
1978
Effects of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent on the cardiovascular and central nervous systems.
1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) has been reported to be a potent… Expand
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1978
1978
Pharmacological properties of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.
1-(2',6'-Dimethylphenyl)-3-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride), a potent, unique antidiarrheal agent… Expand
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1978
1978
Pharmacokinetics and disposition of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent, in rat and monkey.
14C-Labelled 1-(2,6-dimethylphenyl)-3-methylamidinourea hydrochloride (14C-WHR-1142A, lidamidine hydrochloride) was rapidly and… Expand
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1978
1978
Toxicity studies on lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.
The acute oral LD50 of 1-(2,6-dimethylphenyl)-3-amidinourea hydrochloride (WHR-1142A, lidamidine hyrochloride) was 260 (208, 328… Expand
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1978
1978
Analytical-physical profile of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.
The structure elucidation, physical and chemical parameters and hydrolysis kinetics of 1-(2,6-dimethylphenyl)-3-methylamidinourea… Expand
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