WHR-1142A

Known as: WHR- 1142A

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1983

Absence of mutagenic activity of WHR-1142A, lidamidine hydrochloride, in 4 short-term tests for mutagenic/carcinogenic potential.

Jodie Allen, E. Jones, Janet Richardson, Margaret Richold
Mutation research
1983

WHR-1142A, lidamidine hydrochloride, an antidiarrhoeal agent, was tested for possible mutagenic/carcinogenic activity in the Ames… (More)

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1981

[Double-blind evaluation of the effectiveness of lidamidine hydrochloride (WHR-1142A) vs loperamide vs. placebo in the treatment of acute diarrhea].

J G Heredia Díaz, M L Kajeyama Escobar
Salud publica de Mexico
1981

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1979

[Evaluation of the safety and effectiveness of WHR-1142A in the treatment of non-specific acute diarrhea].

J G Heredia Díaz, Isabela Romanha de Alcantara, Amy C Solis
Revista de gastroenterologia de Mexico
1979

A randomized double-blind placebo controlled trial of the safety and efficacy of lidamidine hydrochloride (WHR-1142A) in thirty… (More)

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1978

Effects of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent on the cardiovascular and central nervous systems.

R L Riley, G. N. Mir, G S Rowles, J W Sperow, R L Alioto, J Yelnosky
Arzneimittel-Forschung
1978

1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) has been reported to be a potent… (More)

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1978

In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.

G. N. Mir, R L Alioto, J W Sperow, J R Eash, Jörg Krebs, J Yelnosky
Arzneimittel-Forschung
1978

1-(2,6-Dimethylphenyl)-3-methyl-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) was shown to have potent… (More)

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1978

Pharmacological properties of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.

G. N. Mir, J W Sperow, +4 authors J Yelnosky
Arzneimittel-Forschung
1978

1-(2',6'-Dimethylphenyl)-3-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride), a potent, unique antidiarrheal agent… (More)

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1978

Toxicity studies on lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.

Bo-Yi Chou, G. N. Mir, William Brown, Wayne Rapp, J Yelnosky
Arzneimittel-Forschung
1978

The acute oral LD50 of 1-(2,6-dimethylphenyl)-3-amidinourea hydrochloride (WHR-1142A, lidamidine hyrochloride) was 260 (208, 328… (More)

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1978

Mechanism of action studies of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.

G. N. Mir, J W Sperow, Jörg Krebs, J R Eash, G S Rowles, J Yelnosky
Arzneimittel-Forschung
1978

1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A), lidamidine hydrochloride), a novel antidiarrheal agent… (More)

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1978

Analytical-physical profile of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent.

J J Zalipsky, Changwon Won, Dhiren Patel
Arzneimittel-Forschung
1978

The structure elucidation, physical and chemical parameters and hydrolysis kinetics of 1-(2,6-dimethylphenyl)-3-methylamidinourea… (More)

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1978

Pharmacokinetics and disposition of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent, in rat and monkey.

A F Delong, G. P. Martin, Andreas Polk, Victoria S. Carter, Timea Herczeg
Arzneimittel-Forschung
1978

14C-Labelled 1-(2,6-dimethylphenyl)-3-methylamidinourea hydrochloride (14C-WHR-1142A, lidamidine hydrochloride) was rapidly and… (More)

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WHR-1142A

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WHR-1142A

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