WAY-169916
National Institutes of Health
Papers overview
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A new method for the synthesis of 1H-indazoles from readily available N-tosylhydrazones and nitroaromatic compounds has been…
The bioactivities of the natural steroidal estrogen 17β-estradiol (E2), the synthetic estrogen diethylstilbestrol (DES), and the…
The concept of selective receptor modulators has been established for the nuclear steroid hormone receptors. Such selective…
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the toxicity of 2,3,7,8…
Previous studies have shown that estrogen treatment protects the heart from reperfusion injury. The adverse effects of long-term…
We previously reported on the development of a pathway-selective estrogen receptor (ER) ligand, WAY-169916, that has ER-dependent…
A compound that acts via the oestrogen receptor (ER) to selectively inhibit nuclear factor-κB (NF-κB) without displaying…
A compound that acts via the oestrogen receptor (ER) to selectively inhibit nuclear factor-κB (NF-κB) without displaying…